More from our coverage of the 7th Collaborative Clinical Trials in Anaesthesiology Conference, Prato, Italy. This piece discusses trials in the wake of COVID-19 specifically we focus upon the PROTECT Platform Trial. Presented by Monty Mythen and Kate Leslie with their guests Tom Abbott, anaesthetist and clinical lecturer at Queen Mary University of London and James Glasbey, NIHR Academic Clinical Lecturer in Global Surgery, University of Birmingham and General Surgery Registrar.