Recorded at the 7th Collaborative Clinical Trials in Anaesthesiology Conference, Prato, Italy this piece is a conversation about the current hot topics and research in Anaesthesia. Desiree Chappell speaks with Kate Leslie, Professor, specialist anaesthetist and head of research in the Department of Anaesthesia and Pain Management, Royal Melbourne Hospital, and honorary professorial fellow at the University of Melbourne and Monash University in Australia.