At Chicago's Business School, Zonis teaches courses on International Political Economy, Leadership, and E-Commerce. He was the first professor at the Business School to teach a course on the effects of digital technologies on global business. He also consults to corporations and professional asset management firms throughout the world, helping them to identify, assess, and manage their political risks in the changing global environment. Zonis is a co-founder and Chairman of DSD, a software development company based in Moscow and Chicago. What unites these activities is Zonis' unique awareness of the intersections of politics, economics, and emergent technologies.