Description
In our latest podcast, Modifying the Microbiome to Minimise Pain, Matt talks to Dr Siobhain O’Mahony, a leading academic in microbiome research. Dr O’Mahony has published work within human medicine, examining the link between the microbiome and pain outcomes after surgery. And we ask, ‘How could this translate into our field of veterinary pain management?’
We also touch upon what we should eat ourselves and ask whether we are feeding our pets correctly.
References for shownotes
The gut microbiota as a key regulator of visceral pain (2017)
The gut microbiota in persistent post-operative pain following breast cancer surgery
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11137075/
Stevens, Christina et al. “Gut Microbiome and Osteoarthritis: Insights From the Naturally Occurring Canine Model of Osteoarthritis.” Arthritis & rheumatology (Hoboken, N.J.), 10.1002/art.42956. 19 Jul. 2024, doi:10.1002/art.42956
Stewart, H L et al. “Differences in the equine faecal microbiota between horses presenting to a tertiary referral hospital for colic compared with an elective surgical procedure.” Equine veterinary journal vol. 51,3 (2019): 336-342. doi:10.1111/evj.13010
Stewart, Holly L et al. “Changes in the faecal bacterial microbiota during hospitalisation of horses with colic and the effect of different causes of colic.” Equine veterinary journal vol. 53,6 (2021): 1119-1131. doi:10.1111/evj.13389
Jan S Suchodolski
https://pubmed.ncbi.nlm.nih.gov/34514619/
The Dysbiosis Index (DI) is a validated quantitative PCR assay for canine fecal samples that measures the abundance of seven important bacterial taxa and summarizes the results as one single number.
The DI can be used to assess the microbiome in clinical patients over time and in response to therapy (eg, fecal microbiota transplantation).
Spoiler alert - you need to listen to this podcast to understand if there is a place for subcutaneous methadone in veterinary clinical practice!
In this edition, Matt reviews the first paper that investigated pharmacokinetics of subcutaneous methadone and first raised the question of using this...
Published 08/23/24
Professor Clare Rusbridge is a global thought leader in the management of syringomyelia, Chiari malformation and phantom scratching. To assist vets in treatment of these conditions, Clare has recently updated and released her 2024 treatment algorithms. In this episode, Matt discusses the new...
Published 07/19/24