Does positive thinking work - even if you’re one of the country’s most unlucky people? And revealing how changing your mental state can even improve your immune system. Tim Samuels brings Barrie and Margaret - and their tales of woes - face-to-face with positive thinking gurus. Will they finally manage to alter their fortunes through a shift of attitude? Tim also hears from a leading mind-body expert that having the right type of mental state - based in meaning - can improve survival rates for serious diseases and lead to better immune systems. For extra content, videos and a regular newsletter go to www.bbc.co.uk/allhailkale