Over the past twenty years, Gavi, the Vaccine Alliance, has proven to be a high-impact and resilient global health partnership. Launched at the World Economic Forum in Davos in 2000, Gavi has mobilized its network of government, private sector, and civil society partners to make vaccines affordable and available to millions of children in the world’s lowest-income countries. Yet after years of improvements, immunization coverage has now stagnated in some countries, and the challenges posed by demographic change, urbanization, and conflict all threaten to slow global progress. Gavi’s new strategy for 2021-2025 lays out a plan to confront these challenges and reach the most vulnerable children with vaccines, and the organization will seek funding to help it reach its goals at a pledging conference to be hosted by the United Kingdom in June of 2020. The United States has supported Gavi since 2000, and the Alliance’s contributions to health security and efforts to enable countries to move towards sustainable, self-financed immunization programs resonate with U.S. global health and development goals.   On Monday, February 24, from 2:30 to 4:00pm, the CSIS Global Health Policy Center will host a public event focusing on challenges and opportunities for advancing Gavi's work in this new 2021-2025 phase. Following introductory remarks by CSIS Senior Vice President and Global Health Policy Center Director J. Stephen Morrison, Seth Berkley, CEO of Gavi, the Vaccine Alliance, will deliver a keynote presentation on Gavi’s plans for replenishment and beyond. He will then be joined by Irene Koek, Acting Assistant Administrator for the Global Health Bureau at USAID; Robin Nandy, Principal Advisor & Chief of Immunizations at UNICEF; and Katherine Bliss, Senior Fellow with the CSIS Global Health Policy Center, for a panel discussion examining the role of U.S. support for Gavi as the organization enters its third decade.   Keynote Presentation   Seth Berkley Chief Executive Officer Gavi, the Vaccine Alliance   Introduced by J. Stephen Morrison Senior Vice President and Director CSIS Global Health Policy Center   Panel Discussion   Seth Berkley Chief Executive Officer Gavi, the Vaccine Alliance   Katherine Bliss Senior Fellow CSIS Global Health Policy Center   Irene Koek Acting Assistant Administrator Global Health Bureau USAID Robin Nandy Principal Advisor & Chief of Immunizations UNICEF   Moderated by J. Stephen Morrison Senior Vice President and Director CSIS Global Health Policy Center   This event is made possible through the generous support of the Bill & Melinda Gates Foundation.