Embark on an enlightening journey with us as we uncover the delicate balance between hormones, diet, and longevity. Joined by the esteemed Dr. Robert Lustig, our conversation traverses his transformative work on leptin and obesity, challenging conventional wisdom on weight management. Dr. Lustig's tale of triumph in treating children with hypothalamic obesity underscores a crucial lesson: hormonal regulation can profoundly affect our quality of life and energy levels, setting the stage for a ...

Unlock the secrets to a longer, healthier life with Dr. Nathan Bryan, an esteemed nitric oxide expert. Together, we explore the groundbreaking work that has placed this molecule at the forefront of longevity science. From his early days as a curious student to his innovative contributions alongside Nobel Prize laureates, Dr. Bryan takes us through the intricacies of how nitric oxide impacts everything from cardiovascular health to cellular repair. Delve into the compelling distinction between...

When Grace Price watched "Fed Up," a documentary that exposed the unsettling truths behind our diet, it ignited a spark within her that grew into a fierce crusade for metabolic health awareness. At just 18 years old, this visionary filmmaker is now steering the conversation with her own project, "Cancer: A Food-Borne Illness." Grace has allowed us to included the full 20 minute documentary at the end of this interview.So stay tuned to watch the whole thing for your self.Before we do tha...

Unlock the door to a vibrant future for your brain with guidance from Dr. Austin Perlmutter, as we navigate the complexities of brain health and longevity. Our brains aren't just central to our thoughts and feelings; they dictate the quality of our decisions and, ultimately, our life trajectory. Together, we dissect the perils of 'stuckness'—that all-too-familiar inertia impeding our pursuit of wellness. Dr. Perlmutter offers a treasure trove of insights on mitigating lifestyle habits that co...

Unlock the hidden truths behind the medical curtain as we converse with Dr. Ken Berry about the often-untold realities healthcare professionals face. Our exchange promises to illuminate the dark corners of medical practices, revealing why some doctors might withhold the full spectrum of information. Prepare to have your understanding of traditional medical teachings challenged, as we dissect the significance of lifestyle and nutrition in preventing and managing chronic diseases. This ep...

Unlock the secrets of cognitive rejuvenation as Dr. Heather Sanderson joins us to share a groundbreaking narrative of hope and renewal, inspired by Dr. Dale Bredesen's visionary work. Witness the inspiring transformation of Linda, who, with unwavering dedication and a holistic lifestyle overhaul, remarkably improved from a severe stage of dementia. Our discussion extends beyond the worn path of beta-amyloid focus, venturing into the realms of diet, inflammation control, and the profound effec...

Unlock the transformative secrets to mental wellness with our esteemed guest Dr. Chris Palmer, a Harvard psychiatrist who brings a revolutionary perspective to the table. Together, we unravel how dietary strategies like the ketogenic diet hold the potential to reverse serious mental health issues and delve into personal experiences and clinical success stories that could reshape our approach to mental health care. During our conversation, Dr. Palmer and I explore the metabolic roots of...

Embark on an electrifying journey to the core of our cells with myself, Dr. Robert Lufkin, and a panel of esteemed guests, including Dr. Monisha Bhanote, Sarah Turner, and Dr. Hemal Patel. We're unpacking the enigmatic world of mitochondria, revealing how these microscopic powerhouses fuel every aspect of our health. From the energy surging through your veins to your body's ability to combat aging and disease, our conversations shed light on cutting-edge therapies like red light therapy, the...

Prepare to be inspired by our esteemed guest, Dr. Peter Diamandis, as we explore the realm of extending human lifespans through exponential technologies. His wealth of knowledge, from a background in a medical family to pushing the boundaries of space exploration, sets the stage for an episode packed with innovative ideas. We delve into the exciting world of regenerative medicine, discussing the promising future of placental derived cells and the tiny powerhouses known as exosomes. Dr....

Unlock the secrets of longevity with Dr. Sandra Kaufman, who introduces us to the fascinating world of cellular aging. On our show, we unravel the mysteries of why and how our cells decline with age, with a specific look at post-reproductive evolution's impact on this process. Dr. Kaufman, with her unique blend of expertise in cell biology and anesthesiology, outlines the seven tenets of aging and shares her personal journey that led her to create the Kaufman Protocol, a personalized strategy...

Unlock the mysteries of aging with our fascinating guest, Dr. Nir Barzilai, as we embark on a journey through the science of longevity. This episode promises to reveal the biological secrets that could redefine your approach to living a long, healthy life. Dr. Barzilai, with his wealth of knowledge, decodes the process of antagonistic pleiotropy where the very mechanisms that protect us in youth may become our foes in old age. Together we scrutinize inflammation's role in aging, explore the...

Confronting the silent epidemic of chronic disease, I found liberation not in the latest pharmaceuticals, but in the transformative potential of lifestyle changes. My personal pilgrimage through the gauntlet of ailments such as gout and hypertension revealed a truth that traditional medicine often overlooks: wellness is often rooted in our daily habits. Join me as we unravel the deceptive web spun by common misconceptions surrounding diet and chronic illness. As we unfold the pages of our...

Unlock the secrets to a sharper mind and a healthier life as we navigate the profound insights of Dr. David Perlmutter, a leading neurologist and acclaimed author. Our journey with him reveals the pivotal brain-gut connection that dictates our mental clarity and longevity. Discover why your gut health and diet are not just about waistlines but about safeguarding your brain from the perils of modern living. Through Dr. Perlmutter's expertise, we learn how the everyday choices on our plates...

Unlock the power of your next meal to not only nourish but also rejuvenate and extend your life. I’m thrilled to share the enlightening conversation I had with Dr. Joseph Antoun, CEO of El Nutra and Prolon, who brings a wealth of knowledge from the fields of medicine and nutritional science. Dr. Antoun delves into the intricate ways food can act as our most powerful medicine, highlighting the significant role fasting-mimicking diets play in cellular health and disease prevention. We tackled...

Unlock the secrets to your genetic potential as Dr. Bruce Lipton, a trailblazing biologist in the field of epigenetics, joins us to challenge the notion that our DNA is our destiny. Prepare to be empowered with the knowledge that your environment and belief systems have a profound impact on your biological outcomes. Dr. Lipton's extensive research on stem cells reveals how our cells are influenced by their surroundings, offering a riveting glimpse into how we can actively sculpt our health...

Embark on a transformative exploration of health with Dr. Robert Lufkin, who, through his own battle with health challenges, advocates the profound benefits of lifestyle changes over medications in treating chronic diseases. Our conversation dismantles the deeply-rooted misunderstandings around obesity, diabetes, Alzheimer's, and heart disease. It's not just about what you eat, but the types of macronutrients that shape your well-being. Discover how diet and fasting can do more than just...

Could fasting be the key to unlocking a healthier, longer life? Join us as we sit down with Megan Ramos, co-author of "Life in the Fasting Lane" and a true testament to the healing powers of fasting. Together, we explore her journey from a type 2 diabetes diagnosis to a life of improved metabolic health, unwrapping the layers of how intermittent fasting can combat chronic conditions and pave the way to wellness. This isn't just about shedding pounds; it's about a profound transformation that...

Step into the extraordinary as Marek Piotrowski, once at the helm of corporate giants, now charts a course for uncharted territories of health and longevity. Alongside his son, Marek has traversed the globe, from the blue zones of Okinawa to cutting-edge labs in Shanghai, to unravel the secrets that could add years to your life and life to your years. In today's episode, we unpack their year-long journey, documented in a riveting film, where you'll learn how practical, everyday habits can...

Unlock the mysteries of aging and longevity with the visionary Dr. Aubrey de Grey in our latest podcast episode. His pioneering work in biomedical gerontology offers a roadmap to not just slowing down the aging process, but potentially reversing it. As Dr. de Grey transitions from his origins in computer science, he deciphers our biological clock, revealing how funding from venture capitalists and the crypto-community is accelerating the quest for extended human healthspan. Immerse yourself...

Join Patrick Will as we uncover the unsettling realities lurking within your personal care products and learn how to navigate the maze of nutrition misinformation. Join us as we engage in a fascinating dialogue to expose the stark inconsistencies in cosmetic regulations and dissect the complex interaction between insulin, macronutrients, and our health. By tuning into our conversation, you'll gain a deeper understanding of how the evolution of fruits and vegetables has silently influenced our...

Unlock the mysteries of aging and chronic disease as we navigate the compelling intersection of these conditions with inflammation, guided by the expertise of Dr. Eric Gordon. Our journey begins with the body's double-edged sword—its inflammatory response. Vital for healing yet detrimental when uncontrolled, inflammation presents a paradox in our quest for longevity. Dr. Gordon illuminates the role of mitochondria in this delicate balance, linking the cell danger response to our overall...

Join us on a mind-bending exploration of the human brain, aging, and the untapped potential of psychedelics with our guest, Dr. Jeffrey Becker. As a psychiatrist with a keen interest in natural molecules and their effects on our minds, Dr. Becker brings to the table a fresh perspective on mental health. His insight on the brain as a metabolic organ, the positive impacts of the ketogenic diet, as well as the intriguing world of psychedelics promises to transform the way we think about our...

Got a minute to ponder the fleeting beauty of life and the tantalizing possibility of extending our time here? Come on a journey with us, as we reflect on gratitude, transience, and the magic of potential longevity drugs. In our year-end episode, we're revisiting one of our most engaging topics from the past year - the promising molecules of Rapamycin and Metformin.  Have you ever wondered what would happen if we could use modern medicine to extend our lives? We're taking a deep look at two...

Are you practicing medicine based on outdated teachings? Welcome to an episode that boldly challenges entrenched beliefs in the medical field and brings to light the dynamic nature of medical research.  We'll take a deep dive into Alzheimer's disease, and its intriguing links to metabolic abnormalities. Shifting our focus from the traditional amyloid and plaque model, we'll explore the theory of Alzheimer's as a form of diabetes - termed as type 3 diabetes. Join us as we explore the...

Picture this – you're a teenager, on the brink of exploring life, and you're told you have a brain tumor. That's exactly what happened to our guest, Chris Mirabile, who turned a life-altering experience into a catalyst for personal transformation. Listen in as Chris shares his journey from a brain tumor survivor to a health and wellness advocate, emphasizing the need to consider both short-term and long-term effects of lifestyle choices. His insights on the potential risks associated with...