Dr Glenn McConell chats with Professor Scott Trappe, Director of the Human performance laboratory at Ball State University, Indiana, USA. We spoke about the influence that Scott’s supervisor, the great David “Doc” Costill, has had on exercise physiology (long time Ball State HPL Director before Scott). We then discussed the negative effects of space on the human body and whether exercise can minimize these negative effects. In space slow muscle fibers atrophy more than fast fibers and there is a large shift to fast fiber types. Exercise attenuates this. A very interesting, relaxed, fun chat. @HPLBallState 0:00. Introduction etc3:22. Ball State, David Costill and Scott’s background10:30. Space research: Bob Fitts, David Costill and Scott.14:50. Retesting champion runners 25 plus years later19:16. Space flight experiments, biopsies in Russia etc20:43. Effects of space on physiology, fluid shifts etc27:08. Slow muscle fibers atrophy more than fast fibers29:50. Integrated physiology31:40. Lower body negative pressure/exercise in space37:22. 6 months and longer in space: Moon, Mars40:10. Biopsies within 6-8 hrs after get back from space!44:22. Appetite in space46:09. Exercise around 90 min/day in space47:23. Exercise provides partial protection and less fibre type shifts50:34. Bed rest studies52:10. Bone loss / not much pharmacology in space53:02. Less interfering effects on exercise responses in space55:08. Fiber type shifting with inactivity/space/exercise1:00:30. Hybrid muscle fiber cells. Myosin heavy chains1:04:16. Time course of bone loss/recovery1:06:14. Is exercise before space flights protective?1:07:19. Space travel, exercise and insulin sensitivity1:08:06. VO2 max and the heart after space travel1:10:43. Space flight increases the velocity of muscle contraction1:16:45. Medications in space1:18:00. Eccentric loads in space1:19:04. Huge multi lab NIH exercise research project: MoTrPAC1:28:59. Takeaway messages1:30:43. David Costill: 87 and still training like an athlete!1:34:30. Scott’s exercise training and racing1:37:37. Banter about dos and don’t in the lab1:38:52. Glenn’s Copenhagen sabattical plans/trip to Indiana?1:41:30. Outro (9 secs) Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).Connect with Inside Exercise and Glenn McConell at:Twitter: @Inside_exercise and @GlennMcConell1Instagram: insideexerciseFacebook: Glenn McConellLinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460ResearchGate: Glenn McConellEmail: [email protected] Subscribe to Inside exercise:Spotify: shorturl.at/tyGHLApple Podcasts: shorturl.at/oFQRUYouTube: https://www.youtube.com/@insideexerciseAnchor: https://anchor.fm/insideexerciseGoogle Podcasts: shorturl.at/bfhHIAnchor: https://anchor.fm/insideexercisePodcast Addict: https://podcastaddict.com/podcast/4025218Not medical advice