Dr Glenn McConell chats with Dr Edward Chambers from Imperial College London who is an expert on the gut microbiota, exercise and metabolism. He has shown that some fibre can be fermented to short chain fatty acids (SCFA) by gut microbiota which can influence skeletal muscle metabolism. In addition, these SCFA can affect appetite. He has also shown that exercise and/or carbohydrate ingestion reduces appetite. Important message, eat the recommended amount of fibre. Very interesting work and a fun chat.0:00. Introduction2:21. What is the gut microbiota and why important?4:02. 1.5-2kg of body weight is bacteria throughout one’s gut7:02. CHO in mouth effects brain activity /exercise performance12:34. Meals vs glucose/insulin infusions for muscle glucose uptake14:20. Is all ingested CHO absorbed or partly fermented?16:07. Some fibre fermented to short chain fatty acids (SCFA) by gut microbiota21:35. What kinds of fibre are fermentable22:15. Diet and antibiotics affect your gut bacteria25:06. Establishing a healthy gut microbiome early if life27:44. Effects of the SCFA produced by gut microbiota33:22. SCFA and appetite hormones34:15. Antibiotics/SCFA and endurance capacity34:30. Translation of rodent studies to humans38:45. Effects of acetate on muscle glycogen and fat oxidation41:58. How quickly can diet affect gut microbiota?43:29. Probiotics, microbiota, exercise and upper airway infections46:17. Need sufficient fibre to ferment49:00. Athletes concerned with gas/bloating from high fibre intakes51:20. Lean vs obese people and gut microbiota52:25. CHO ingestion with and without exercise and appetite. GLP-11:00:45. Lactate, exercise and appetite1:02:00. Succinate from muscle and gut microbiota and appetite1:02:59. Exercise plus GLP-1 agonists for weight loss1:04:00. Variability in the effects of exercise on appetite/weight loss1:07:42. Yo Yo effects of exercise and diet on weight loss1:09:47. CHO and gut microbiota during the Tour de France1:12:40. Gut microbiota and mental health1:14:52. Are all gut microbiota good for us? /fatty liver1:17:20. High fibre intake associated with higher muscle mass and strength1:21:30. Aging and gut microbiota, need to keep eating fibre1:24:35. Exercise training changes the gut microbiota1:28:25. Sex differences in the gut microbiota1:31:28. Diet with and without exercise and gut microbiota1:33:05. Takeaway messages1:35:16. Outro (9 seconds)Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).Connect with Inside Exercise and Glenn McConell at:Twitter: @Inside_exercise and @GlennMcConell1Instagram: insideexerciseFacebook: Glenn McConellLinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460ResearchGate: Glenn McConellEmail: [email protected] to Inside exercise:Spotify: shorturl.at/tyGHLApple Podcasts: shorturl.at/oFQRUYouTube: https://www.youtube.com/@insideexerciseAnchor: https://anchor.fm/insideexerciseGoogle Podcasts: shorturl.at/bfhHIAnchor: https://anchor.fm/insideexercisePodcast Addict: https://podcastaddict.com/podcast/4025218Not medical advice