Audry Hawkins is back to discuss antimicrobial stewardship in pneumonia. She starts with comparing differences in guidelines and recent primary literature on empiric treatment of pneumonia. Hawkins then evaluates appropriate empiric step-down therapy and durations and after, discusses the nuances in guideline recommendations for pneumonia. Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more...

Crystal Heishman presents an introduction on the broad topic of Infection Prevention. Heishman presents how to identify methods to prevent infectious disease transmission and how to implement device related infection prevention strategies for CAUTI and CLABSI. After, she discusses appropriate testing requirements for C.Diff.Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our...

Dr. Ben Rogers presents a lecture on reflux by discussing a classic presentation of reflux as well as testing. Dr. Rogers emphasizes modifying care and diagnosis towards each patient with their own unique symptoms.Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page.Disclaimers©2016 LouisvilleLectures.org

In this presentation, Dr. Ryan Doster gives an introduction to diagnostic stewardship after last week's discussion on antimicrobial stewardship. After, Audry Hawkins, PharmD, BCIDP, returns to give an overview on blood culture. Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page.Disclaimers©2016 LouisvilleLectures.org

In this introduction to antimicrobial stewardship, Audry Hawkins first lists untoward effects of antibiotic use. She then describes antibiotic stewardship principles, goals, and strategies. After, she recognizes changes in the regulatory roadmap and national landscape of antimicrobial stewardship over the past few years, including requirements for accreditation for stewardship programs. Lastly, she identifies proven benefits of antimicrobial steward ship; and finally, Sarah Moore reviews the...

Dr. Malika Rawal presents Adrenal Insufficiency by first answering the question: What Is Adrenal Insufficiency? She then reviews its causes as well as some basics of cortisol. After, Dr. Rawal discusses testing and treatment.Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page.Disclaimers©2016 LouisvilleLectures.org

Dr. David Armstrong presents Systemic Lupus Erythematosus by first presenting a case. He then discusses the history of SLE as well as the different kinds of lupus. After, he differentiates between systemic lupus erythematosus and drug-induced lupus. And finally, Dr. Armstrong gives examples of treatment and drug induced lupus management.Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more...

In Glomerular Disease Part One, Dr. Dawn Caster begins by discussing the classifications of common renal pathology and after, focuses on nephrotic syndrome. Dr. Caster gives an overview of nephrotic syndrome and its associated abnormalities as well as the mechanisms of the thrombophilic state in nephrotic syndrome. In part two. Dr. Caster will discuss Glomerulophritis.Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end...

Alexa Filley, PharmD, delivers a lecture on Common HIV Regimens and Opportunistic Infection Prophylaxis. She first reviews common human immunodeficiency virus treatment regimens and after, discusses patient/medication characteristics to guide therapy selection. Filley concludes her presentation by reviewing and applying Department of Health and Human Services (DHHS) Guidelines on opportunistic infection prophylaxis in patients with HIV.Some items in this lecture may have come from the...

Dr. Malika Rawal gives an overview on Gender-Affirming Hormone Therapy. Dr. Rawal first discusses the different types of transition as well as general definitions and after, lists terms physicians should and should NOT use when treating patients. Dr. Rawal presents what a visit would look like and how to work with the patient, expectations of hormone therapy, and the physical effects of hormone therapy for feminizing hormone therapy along with masculinizing hormone therapy.Some items in this...

Dr. David Armstrong presents Seronegative Spondyloarthropathies and emphasizes these take home points:- HLA-B27 does not diagnose SNSAs- Inflammatory back pain improves with exercise- Red eye with decreased visual acuity needs slit lamp- Nail pitting correlates with psoriatic arthritis - NSAIDs help everything except enteropathic arthritis Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more...

Dr. Chris Reed presents an overview of congenital arrhythmogenic pathologies by first focusing on two families of diseases: structural and conduction. He then discusses pathophysiology and cause of disease and after, the diagnostic workup and what to include in a consultation. Finally, Dr. Reed presents management plans and when to pursue intervention.Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture....

Our new Chair of the Department of Medicine, Dr. Kim Williams, presents his first Grand Rounds on the topic of Nutrition, Health Equity, and CV Mortality. First, Dr. Williams discusses some of the main issue in the United States including being its expensive and broken healthcare system. With the expectance of an increase in cardiovascular disease and stroke mortality in the US in the upcoming decades, particularly in minority groups, Dr. Williams believes our poor nutrition promotes and...

Dr. Laura Bishop presents "Opiate Use Disorder in the Inpatient Setting: To Bup or Not to Bup with Dr. Bishop" by first examining the practice for adjustments to create space of destigmatizing patients with SUDS. She then discusses the symptoms of opiate withdrawal as well as the pharmacology of buprenorphine and its efficacy/safety in treating opiate use disorder. Dr. Bishop then identifies patients who would benefit from buprenorphine and constructs a plan of care for patients with opiate...

Dr. Regan Wade presents "Heart Failure Pharmacology" by first reviewing heart failure pathophysiology as it relates to pharmacotherapy. She then discusses guideline directed therapy and other agents indicated to optimize HF care. After, Dr. Wade evaluates literature related to new therapies and indications for medications in patients with heart failure. Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the...

Dr. Sara Ellingwood presents a talk on Asthma starting with its definition and phenotypes. She discusses making a diagnosis, differential diagnosis, and management. After, Dr. Ellingwood ends with a discussion on when to refer. Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page.   Disclaimers ©2016 LouisvilleLectures.org

Dr. Forest Arnold returns to present "COVID-19 Vaccines: Wows and Woes" today on Louisville Lectures. In this presentation, Dr. Arnold gives an overview of COVID-19 and vaccines. He then discusses a case of potential thrombosis due to the Johnson & Johnson vaccine as well as the pathophysiology of vaccine-induced immune thrombotic thrombocytopenia (VITT). After, he presents the CDC Advisory Committee on Immunization Practices and the efficacy of vaccines in light of variants. And finally,...

Our Chief Medical Resident for Education, Dr. Samuel Reynolds returns to give an introduction on abstract writing. He begins by describing an abstract and its importance. After, he discusses the general process of abstract writing. Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page. Disclaimers ©2016 LouisvilleLectures.org

Dr. Nina Vasavada gives an Acid Base Core Lecture by first reviewing dietary sources of acids and alkali. She then reviews renal and non renal mechanisms of maintaining acid/base equilibrium. After, she discusses practice questions.   Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page. Disclaimers ©2016 LouisvilleLectures.org

Our Chief Medical Resident for Education, Dr. Samuel Reynolds, presents “Basic Science: Molecular Biology in Cardiovascular Disease”. He discusses the basis of Cardiovascular Disease from a molecular standpoint and emphasizes how arrhythmia and cardiac conduction impairment relates to coronary artery disease and how the development of structural heart disease can mean problems for our heart’s ability to conduct electrical signals. Please note: this presentation took place in our Didactics...

Dr. Jennifer Olges presents "Health Disparities: Food Insecurity and Food Deserts" by first defining food insecurity and food deserts. She then compares and contrasts hunger and food insecurity and describes the scope of the issue in Louisville/Jefferson County as well as in the clinic population. After, Dr. Olges describes the clinical implications of food insecurity and finally, reviews the process for accessing the food bank in the AIM clinic.   Some items in this lecture may have come...

Dr. Aaditya Chandramouli presents Part One of Sepsis and Sepsis Shock. In this Little Lecture, Dr. Chandramouli discusses the definitions and diagnosis of Sepsis and Sepsis Shock. Stay tuned for next time when he presents the Part Two - Management of Sepsis Shock. Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page. Disclaimers ©2016 LouisvilleLectures.org

Dr. Christopher Chan presents an Introduction to Mechanical Ventilation by first defining respiratory physiology and indications for mechanical ventilation. He then presents the initial parameters/modes of ventilation as well as supportive care. After, Dr. Chan discusses troubleshooting the vent, weaning, successful liberation from the vent, and finally, the checklist.   Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the...