In episode 59 of MASS Office Hours, Dr. Eric Trexler is joined by Dr. Eric Helms to discuss practical implications of strength asymmetries, purportedly anti-catabolic supplements, troubleshooting pain while lifting, the lifting volume needed to maintain gains during a weight loss phase or period of reduced training, and much more. The MASS crew goes live for Office Hours every Wednesday night at 7pm eastern time. Be sure to join us for a future episode! If you'd like to submit a question ahead of time, please use this link: https://massresearchreview.com/office-hours/ Time stamps: 0:00 Intro 9:27 How to program unilateral exercises when strength asymmetries are present 14:25 Supplements with anti-catabolic or anti-sarcopenic effects? 20:23 Berberine supplementation 27:08 Helms’ calf-stretching hypertrophy boot 29:06 Addressing hip pain during deadlifts 45:41 Revisiting Helms’ hypertrophy boot 48:40 Elevating legs to facilitate recovery? 55:37 Is 4 sets per week enough volume to maintain muscle during a fat loss phase? 1:16:26 Does edema/swelling skew results of high-volume training studies? 1:22:46 Do you have to hit macro targets every day?