The Filtrate: Joel Topf Swapnil Hiremath Matt Sparks Editor: Joel Topf Show Notes: The 2010 RFN Top Nephrology Stories The 2021 NephJC Top Nephrology Stories Number 10: AKIKI AKIKI 2 in The Lancet AKIKI 2 in NephJC AKIKI 2 on Freely Filtered Number 9: Effect of Salt Substitution on Cardiovascular Events and Death The Salt Substitute and Stroke Study (SSaSS) in the NEJM The Salt Substitute and Stroke Study (SSaSS) in NephJC FDA Issues Final Guidance Regarding Use of an Alternate Name for Potassium Chloride in Food Labeling Number 8: AURORA, voclosporin for Lupus Nephritis Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1) in the Lancet AURORA 1 on NephJC AURORA 1 on Freely Filtered Number 7: FIGARO trial of finerenone for CV outcomes Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes in the NEJM Rates of Hyperkalemia after Publication of the Randomized Aldactone Evaluation Study by David Juurlink Joel’s intermission FDA Rejections Tricida’s Veverimer Roxadustat Bardoxolone Tenapanor Number 6: Pig Kidney Transplant. As covered in the New York Times Clinical Pig Kidney Xenotransplantation: How Close Are We? from JASN Number 5: KDIGO Blood Pressure Guidelines KDIGO Guidelines As discussed in NephJC And on Freely Filtered Matt’s article on ACCORD he wrote for RFN as a fellow Number 4: Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease (CLICK) CLICK in the NEJM CLICK on NephJC CLICK on Freely Filtered Number 3: Dapagliflozin helps IgA nephropathy The Lancet FDA OKs First Proteinuria Drug for IgA Nephropathy: delayed released budesonide Number 2: New eGFR formulas, now race free. New Creatinine- and Cystatin C–Based Equations to Estimate GFR without Race in the NEJM Number 16: Fixing ADPKD in mice Renal plasticity revealed through reversal of polycystic kidney disease in mice in Nature Genetics Press release from Yale Number 1: KDIGO GN Guidelines PDF in Kidney International NephJC Discussion Last Month in Nephrology skeptical of all the Rituximab Tubular Secretions Overcooked! All You Can Eat Lego Porsche 911 Lego Baby Yoda (Grogu) Beyblades