Dr. Gregg Day talks with Dr. Kathryn T. Hall about the complexities of the placebo effect, its variability among patients, and the genetic factors that influence responses to placebo treatments.  Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Dr. Ahmad Nehme about the complexities of diagnosing and differentiating between cerebral amyloid angiopathy-related inflammation and biopsy-positive primary angiitis of the central nervous system. Read the related article in Neurology. Disclosures can be found at Neurology.org.

In the concluding segment of this two-part series, Dr. Justin Abbatemarco talks with Dr. Jennifer L. Orthmann-Murphy about genetic leukodystrophies and the increasing recognition of these disorders in adult neurology, the importance of genetic testing, and the evolving treatment landscape.  Read the related articles in Neurology and CHS Perspectives.  Disclosures can be found at Neurology.org.

In the first part of this two-part series, Dr. Justin Abbatemarco talks with Dr. Jennifer L. Orthmann-Murphy about a practical approach to genetic leukodystrophies, focusing on the importance of genetic testing, identifying red flags in patients, and navigating the complexities of hereditary spastic paraplegia. Read the related articles in Neurology and CHS Perspectives. Disclosures can be found at Neurology.org.

The November 2024 replay features four episodes dedicated to brain health. It kicks off with an interview with Dr. Nicoline Schiess, who discusses the World Health Organization (WHO) Brain Health Unit. Next, Dr. Katrin Seeher delves into the global burden of neurological conditions and the WHO’s strategies to enhance care and awareness. The third segment features Dr. Natalia Rost who introduces and highlights the American Academy of Neurology’s (AAN) groundbreaking brain health initiative....

Dr. Justin Abbatemarco talks with Drs. Marius Ringelstein and Ilya Ayzenberg about the effectiveness and safety of Eculizumab in routine clinical care. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Drs. Messoud Ashina and Andrea Cipriani about all licensed drug interventions as oral monotherapy for the acute treatment of migraine episodes in adults. Read the related article in the BMJ. Disclosures can be found at Neurology.org.  

Dr. Greg Cooper talks with Dr. Clifford R. Jack Jr about objective criteria for diagnosis and staging Alzheimer disease, highlighting recent advancements in biomarkers to bridge the gap between research and clinical practice. Read the related article in Alzheimer's Association. Disclosures can be found at Neurology.org.

Dr. Gordon Smith talks with Dr. Whitley Aamodt about end-of-life care for patients with neurodegenerative diseases, focusing on healthcare utilization, hospice enrollment, and the importance of early conversations about care preferences. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Kait Nevel talks with Dr. Oumaima Aboubakr about the prevalence of epilepsy in primary CNS lymphoma, to identify factors associated with epilepsy, and to investigate the prognostic significance of seizures in PCNSL. Read the related article in Neurology®. Disclosures can be found at Neurology.org.

In the final part of this three-part series, Dr. Stacey Clardy talks with Drs. Elisabeth Bik and Matthew Schrag about the challenges posed by AI in generating fraudulent research, the importance of cultural solutions to uphold scientific integrity, and the need for modernized data management practices in research. Read the related article in Undark.  Disclosures can be found at Neurology.org.

In part two of this special three-part series, Dr. Stacey Clardy talks with Drs. Elisabeth Bik and Matthew Schrag about the processes involved in addressing concerns about research integrity, covering the role of public platforms, using social media for awareness, identifying potential research fraud, and the need for cultural change within the scientific community to prioritize ethical practices. Read the related article in Undark. Disclosures can be found at Neurology.org.

In the first part of this special three-part series, Dr. Stacey Clardy talks with Drs. Elisabeth Bik and Matthew Schrag about critical issues surrounding research integrity and misconduct. Read the related article in Undark. Disclosures can be found at Neurology.org.

Dr. Farrah Mateen talks with Dr. Katrin Seeher about the significant global burden of neurologic conditions, which affects over 3.4 billion people worldwide, and the strategies the WHO is implementing to improve care and awareness. Read the related article in The Lancet Neurology. Disclosures can be found at Neurology.org.  

In the October 2024 replay features four episodes on approaches to clinical diagnosis of parkinsonism. The episode starts off with Dr. Colin Hoy discuss the concept of prodromal Parkinson disease and the ethical considerations surrounding its diagnosis. The episode leads into a conversation with Dr. Chris Gibbons discussing skin biopsies to detect phosphorylated α-synuclein. In the third episode Drs. Michiko K. Bruno and Lawrence Golbe about a practical diagnostic algorithm for atypical...

Dr. Jeff Ratliff talks with Drs. Nanditha Rajamani and Andy Horn about the challenges faced in current deep brain stimulation practices and the potential for data-driven approaches to enhance treatment outcomes. Read the related article in Nature Communication. Disclosures can be found at Neurology.org.

Dr. Shuvro Roy talks with Dr. Anne Louise Oaklander about the big-picture takeaways for clinicians in the context of managing small-fiber neuropathy.  Read the related article in Neurology® Neuroimmunology & Neuroinflammation. Disclosures can be found at Neurology.org.

Dr. Dara Albert talks with Dr. Jaclyn M. Martindale about the differences in gender representation among leadership positions and award recipients within the Child Neurology Society. Read the related article in Neurology®. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Drs. Michiko K. Bruno and Lawrence Golbe about a practical diagnostic algorithm for atypical parkinsonian disorders, emphasizing the importance of recognizing these conditions in clinical practice. Read the related article in Neurology: Clinical Practice. Disclosures can be found at Neurology.org.  

Dr. Gordon Smith talks with Drs. Shahar Shelly and Teerin Liewluck about the correlation between CMAP duration and myosin loss and their effect on mortality by comparing between patients with CIM with and without myosin loss. Read the related article in Neurology.  Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Dr. Messoud Ashina about the biology of PACAP, its significance in relation to migraines, and its potential as a novel therapeutic approach. Read the related article in The New England Journal of Medicine. Disclosures can be found at Neurology.org.

Dr. Amy Gelfand talks with Dr. Matthew Bender about the possible association between glymphatic outflow and extent of transverse sinus stenosis in patients with intracranial hypertension. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. David Perez talks with Dr. Glenn Nielsen about the effectiveness of physiotherapy in treating functional motor disorder and to determine the best approach for physiotherapy treatment. Read the related article in The Lancet.  Disclosures can be found at Neurology.org.

Dr. Stacey Clardy talks with Dr. Mary Schroth about the revised SMA recommendations, treatment options available, treatment outcomes, and the future of SMA research and care. Read the related article in Neurology: Clinical Practice.  Disclosures can be found at Neurology.org.