Dr. Rajesh Rao speaks with Dr. Jasmine H. Francis on whether sequencing of plasma-derived ctDNA can noninvasively diagnose ocular-involving histiocytosis. From her Ophthalmology Science article, “Plasma-Derived Cell-Free DNA for the Diagnosis of Ocular-Involving Histiocytosis.” Plasma-Derived Cell-Free DNA for the Diagnosis of Ocular-Involving Histiocytosis. Francis, Jasmine H. et al. Ophthalmology Science, Volume 4, Issue 5.

Can artificial intelligence distinguish between pseudopapilledema and true papilledema in children? Dr. Drew Carey interviews author Dr. Melinda Y. Chang on whether AI can be used to improve the diagnostic process in children with abnormal optic nerves and concern for elevated intracranial pressure. From her Ophthalmology Science article, “Artificial Intelligence to Differentiate Pediatric Pseudopapilledema and True Papilledema on Fundus Photographs” Artificial Intelligence to Differentiate...

Does primary trabeculectomy or medical treatment produce better outcomes in terms of quality of life, clinical effectiveness, and safety in patients with advanced glaucoma? Dr. Drew Carey interviews Dr. Anthony J. King on the results of his recent study asking this question published in Ophthalmology, “Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study.” Evaluating Primary Treatment for People with Advanced Glaucoma....

How has ophthalmology medical education changed over time in medical school curriculums? Dr. Edmund Tsui speaks with Drs. Ashish Agar and Sascha Spencer on their review of global trends in medical school ophthalmology education from their Ophthalmology article, “A Systematic Review of Ophthalmology Education in Medical Schools: The Global Decline.” A Systematic Review of Ophthalmology Education in Medical Schools. Spencer, Sascha K.R. et al. Ophthalmology, Volume 131, Issue 7, 855 – 863. ...

Ophthalmologists are not spared from the opioid epidemic. Recent studies have shown that opioids continue to be prescribed after ophthalmic surgeries. Dr. Drew Carey interviews Dr. Matthew R. Starr on his retrospective study published in Ophthalmology, “Hospitalization, Overdose, and Mortality After Opioid Prescriptions Tied to Ophthalmic Surgery.” Hospitalization, Overdose, and Mortality After Opioid Prescriptions Tied to Ophthalmic Surgery. Thao, Viengneesee et al. Ophthalmology, Volume...

The RID-MyC assay, a CRISPR/Cas12a-based test, offers swift and reliable detection of Fungal Keratitis, enhancing diagnostic capabilities at point-of-care settings. Dr. Rajesh Rao interviews Dr. Siddharth Narendran on the development of this assay from his Ophthalmology Science article, “Development and Clinical Evaluation of a CRISPR/Cas12a-Based Nucleic Acid Detection Platform for the Diagnosis of Keratomycoses.” Development and Clinical Evaluation of a CRISPR/Cas12a-Based Nucleic Acid...

Dr. Matt Feng is joined by Dr. Thomas H. Dohlman to discuss the effectiveness of topical and subconjunctival bevacizumab in suppressing vascularization in graft and host bed after high-risk corneal transplantation, from his Ophthalmology Science article “Suppression of Neovascularization by Topical and Subconjunctival Bevacizumab After High-Risk Corneal Transplantation” Suppression of Neovascularization by Topical and Subconjunctival Bevacizumab After High-Risk Corneal Transplantation....

What does hearing dysfunction have to do with an ophthalmology podcast? Listen up and find out as Dr. Drew Carey interviews Dr. Jamie A. Keen and Dr. Erin M. Shriver on the risks of using teprotumumab to hearing function in treatment of thyroid eye disease. From their article “Frequency and Patterns of Hearing Dysfunction in Patients Treated with Teprotumumab.” Frequency and Patterns of Hearing Dysfunction in Patients Treated with Teprotumumab. Keen, Jamie A. et al. Ophthalmology, Volume...

Dr. Matt Feng interviews Drs. Bita Momenaei and Jason Hsu on the incidence, timing, risk factors, and outcomes of recurrent retinal detachment after phacoemulsification, from their Ophthalmology Retina article, “Incidence and Outcomes of Recurrent Retinal Detachment after Cataract Surgery in Eyes with Prior Retinal Detachment Repair.” Incidence and Outcomes of Recurrent Retinal Detachment after Cataract Surgery in Eyes with Prior Retinal Detachment Repair. Momenaei, Bita et al. Ophthalmology...

Private equity (PE) firms acquired over 200 ophthalmology and optometry practices in the United States from 2021 through 2019. Dr. Rajesh Rao interviews author Dr. Gary Joseph Lelli about the implications of this trend and influence of PEs on care use and spending, from his Ophthalmology article, “Association of Private Equity Firm Acquisition of Ophthalmology Practices with Medicare Spending and Use of Ophthalmology Services.” Association of Private Equity Firm Acquisition of Ophthalmology...

X-linked retinoschisis is a relatively common inherited retinal degenerative disease that almost exclusively affects males. No curative medical therapy is available for this condition, however topical and oral carbonic anhydrase inhibitors have been used  for the management of cystoid fluid collections. Dr. Drew Carey interviews authors Dr. Jonathan Hensman and Dr. Camiel J.F. Boon on the results of their Ophthalmology Retina article, “Efficacy of Carbonic Anhydrase Inhibitors on Cystoid...

Uveitis is a heterogenous group of inflammatory eye diseases for which current cytokine-targeted immune therapies are effective for only a subset of patients. Dr. Edmund Tsui is joined by Dr. Lynn M. Hassman and MD/PhD student Joseph B. Lin to explore potential common underlying mechanisms that exist for immune cell recruitment in uveitis in their Ophthalmology Science article, “Aqueous macrophages contribute to conserved CCL2 and CXCL10 gradients in uveitis” Aqueous Macrophages Contribute...

Vitamin A deficiency is the leading cause of preventable childhood blindness worldwide, but how does this deficiency present itself in a clinical setting? Dr. Drew Carey finds out as he interviews Dr. Nieraj Jain, author of “Characteristics of Vitamin A Deficiency Retinopathy at a Tertiary Referral Center in the United States.” Characteristics of Vitamin A Deficiency Retinopathy at a Tertiary Referral Center in the United States. Levine, David A. et al. Ophthalmology Retina, Volume 8, Issue...

An analysis of the IRIS® Registry shows IOL exchanges are increasing over time with vision improving 60% of the time, but worse visual outcomes associated with greater age, worse baseline vision, Black race, Hispanic ethnicity, Medicaid insurance, smoking, and concurrent vitrectomy. Dr. Matt Feng sits with authors Drs. David F. Chang and Fasika A. Woreta to discuss these findings and more from their Ophthalmology article, “Visual Acuity Outcomes and Complications after Intraocular Lens...

The Department of Health and Human Services, Health Resources and Services Administration’s Health Workforce Simulation Model forecasts a sizeable shortage of ophthalmology supply relative to demand by the year 2035, with substantial geographic disparities. Dr. Edmund Tsui is here with author Dr. Sean T. Berkowitz to breakdown the implications of this shortage from his recent Ophthalmology article, Ophthalmology Workforce Projections in the United States, 2020 to 2035. Ophthalmology...

Scleral buckling is a common surgical procedure for the repair of rhegmatogenous retinal detachment. The association between scleral buckling and angle-closure glaucoma is well-documented. However,the influence of scleral buckling on the development and progression of open-angle glaucoma is less well understood. Dr. Lori Provencher interviews Dr. Arthur J. Sit on the effect of scleral buckle surgery on ocular biomechanics and aqueous humor dynamics from his Ophthalmology Glaucoma article,...

Neuro-ophthalmology consultations are critical to the diagnosis and management in the hospital setting. Prompt consultation prevents diagnostic errors and improves patient outcomes. The scarcity of neuro-ophthalmologists means that the increasing outpatient demand cannot be met, prompting many emergency department referrals by non–neuro-ophthalmologists. Dr. Drew Carey discusses this shortage of neuro-ophthalmologists and the need for technological and diagnostic aids for greater outpatient...

Syphilis is often known as the “the great masquerader” because it can mimic symptoms and look like a wide array of other diseases. Dr. Edmund Tsui interviews Dr. Michael Huvard to get to the bottom of how acute syphilitic posterior placoid chorioretinopathy presents itself in eyes and the outcomes for these patients, from his Ophthalmology article “Clinical Characteristics and Visual Outcomes of Acute Syphilitic Posterior Placoid Chorioretinopathy” Clinical Characteristics and Visual...

Dr. Drew Carey sits down with Dr. Thomas V. Johnson to discuss the work of the RReSTORe Consortium in the field of regenerative medicine as applied to optic neuropathies from his Ophthalmology Science article, “The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, & Optic Nerve Regeneration (RReSTORe) Consortium.” For more of the Ophthalmology Science special issue on Neuroprotection, Neuroenhancement, and Neuroregeneration visit...

Endothelial keratoplasty (EK) procedures have become the preferred method of corneal transplantation in the United States. As the frequency of EKs increase, so do associated costs. Dr. Matt Feng interviews Drs. David S. Portney and Shahzad I. Mian about their recent analysis to assess for differences in surgical costs and surgery length based on type of EK, use of preloaded grafts, and performance of simultaneous cataract surgery with EK from their Ophthalmology article “Cost Drivers of...

The Primary Tube Versus Trabeculectomy Study is a multicenter randomized clinical trial comparing the safety and efficacy of tube shunt surgery and trabeculectomy with mitomycin C in eyes without previous ocular surgery. Dr. Lori Provencher sits down with authors Dr. Sara J. Coulon and Dr. Steven J. Gedde to discuss the results of this trial from their Ophthalmology Glaucoma article, “Outcomes of Glaucoma Reoperations in the Primary Tube Versus Trabeculectomy Study.” Outcomes of Glaucoma...

Myelin oligodendrocyte glycoprotein-related optic neuritis is typically associated with good visual outcome in most patients, but poor outcomes are reported in 15% to 36.8% of patients. Dr. Drew Carey sits down with Dr. Edward Margolin to discuss the possible factors associated with poor outcomes, from his Ophthalmology article, “Predictors of Poor Visual Outcome in MOG-related Optic Neuritis.” Predictors of Poor Visual Outcome in Myelin Oligodendrocyte Glycoprotein-Related Optic Neuritis....

Recorded live at AAO 2023 and we’re myth busting common ophthalmologic misconceptions of the anterior segment. Drs. Drew Carey and Matt Feng interview Dr. Todd Margolis on his recent Ophthalmology editorial, “Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology.” He shares bonus myths not in the editorial, and takes questions from the audience. (Producer’s note: Please excuse the audio quality. This episode was recorded on the convention center floor...

One-third of US ophthalmologists left at least one practice from 2014-2021. What are the factors behind this high turnover rate, how does this affect patient care, and what can be done to stabilize the workforce? Dr. Rajesh Rao interviews Dr. Ravi Parikh about his Ophthalmology article, “Ophthalmologist Turnover in the United States: Analysis of Workforce Changes from 2014 through 2021.” Ophthalmologist Turnover in the United States. Patel, Prem N. et al. Ophthalmology, Volume 130, Issue 9,...