A Doctor's Mission: How Dr. Scoles Used Genetics to Transform Patient Care with Dr. Lyndell Scoles In this episode, we explore pharmacogenomics, also known as genetic pharmaceutical profiling with Dr. Lyndell Scoles with MDVIP. He’s an early pioneer in using genetic testing to optimize medication choices. With over 30 years of experience in internal medicine, Dr. Scoles shares how genetic pharmaceutical profiling helps determine which medications will work best for each patient based on their unique genetic makeup. He presents compelling examples of how this approach has prevented hospitalizations and improved patient outcomes, including cases of heart failure prevention and depression treatment. We also discuss why this hasn't been widely adopted yet in medical practice, despite its potential to save billions in healthcare costs. Note: As our first in-person recording, you may notice some echo and compressed audio quality in portions of the conversation - we appreciate your understanding as we continue to improve our in-person recording setup. Timestamps: 00:02:49 - Dr. Scoles begins explaining his journey into pharmacogenomics and why he started implementing it in his practice 00:08:28 - Description of how genetic testing is done through cheek swabs and the three-category report system 00:25:30 - Powerful patient case study about adjusting antidepressant dosing based on genetic testing 00:29:54 - Discussion of Metoprolol case studies and the 8% of patients who can't metabolize it properly 00:45:34 - Moving patient story about treating a 13-year ulcer patient successfully using genetic insights 00:50:35 - Resources for physicians to learn more about pharmacogenomics 00:52:43 - Contact information and closing thoughts Dr. Lyndell Scoles 5734246494 https://www.mdvip.com/doctors/lyndellscolesmd [email protected] Dr. Lyndell Scoles is a dedicated MDVIP-affiliated physician with over three decades of experience in internal medicine, renowned for his compassionate, patient-centered approach to healthcare. A strong advocate for personalized medicine, Dr. Scoles has integrated pharmacogenomics—also known as genetic pharmaceutical profiling—into his practice, completing this innovative testing for over 600 patients. This approach empowers him to tailor treatments to the unique genetic makeup of each individual, enhancing outcomes and minimizing adverse effects. Dr. Scoles graduated Magna Cum Laude as valedictorian from the University of Missouri School of Medicine, where he earned his Doctorate of Medicine in 1990. He completed his residency in Internal Medicine at the same institution and holds certifications from the American Board of Internal Medicine and the International Society of Clinical Densitometry. Throughout his career, Dr. Scoles has held numerous leadership positions, including Chief of Internal Medicine at Boone Hospital Center, and served as Medical Director for several care facilities, including nursing homes and Alzheimer's care units. His expertise and dedication to excellence have earned him numerous accolades, such as being named a Castle Connolly Top Doctor (2022–2024) and appearing in Inside Columbia’s Medical Guide as one of Columbia’s Favorite Doctors (2016). Dr. Scoles is a member of esteemed professional societies, including the American Medical Association and the American Society of Internal Medicine. His practice is guided by the principle of treating the whole person—balancing physical, mental, and spiritual wellness—and building meaningful partnerships with his patients to achieve optimal...