A Doctor's Mission: How Dr. Scoles Used Genetics to Transform Patient Care with Dr. Lyndell Scoles In this episode, we explore pharmacogenomics, also known as genetic pharmaceutical profiling with Dr. Lyndell Scoles with MDVIP. He’s an early pioneer in using genetic testing to optimize medication choices. With over 30 years of experience in internal medicine, Dr. Scoles shares how genetic pharmaceutical profiling helps determine which medications will work best for each patient based on their...

Ep. 15 - Beyond One-Size-Fits-All: The Science of Drug-Gene Interactions with Michelle Beckwith This episode features Michelle "Shelly" Beckwith, a genetics pioneer since the 1990s who worked on the Human Genome Project. She breaks down how pharmacogenetic testing helps optimize medication choices by analyzing how patients' genetic variations affect drug metabolism. The discussion covers testing methods, insurance challenges, and the real-world implementation of pharmacogenetics in clinical...

Genotyping vs. Sequencing: What's the Difference? In this episode, Dr. William Stanford, Dr. Yelena Bykhovskaya and Taylor Cu discuss various genetic testing methods. The conversation compares genotyping, exome sequencing, and whole genome sequencing, with an emphasis on whole genome sequencing, which provides the most comprehensive genetic information. Timestamps: 00:03:22 - Discussion begins on what popular genetic testing companies use (genotyping) 00:05:09 - Explanation of how genotyping...

In this episode, Dr. Yelena Bykhovskaya, Chief Scientific Officer at Biography Health, shares her expertise in genetics. We explore the importance of both polygenic and monogenic risk scores in patient care. The conversation underscores the value of combining cutting-edge genetic analysis with traditional clinical factors in the evolving field of precision medicine, emphasizing the need for a comprehensive approach to patient care. Resources...

How Doctors are Using Genetic Data to Transform Patient Care with Philip Bretsky MD PhD MPH FACP In this episode, we're joined by Dr. Philip Bretsky, a board-certified internist from Santa Monica with expertise in epidemiology and Alzheimer's research. Dr. Bretsky discusses how precision medicine is transforming healthcare by integrating genetics, biomarkers, and lifestyle factors. He explores the challenges and opportunities in implementing this approach, the evolving role of general...

Redefining the Healthcare Model: Insights from 20-Year Executive Lucy Janoyan In this episode, we're joined by special guest Lucy Janoyan, Chief Strategy Officer at Biography Health. With over two decades of healthcare executive experience, Lucy explores the transition from reactive to proactive healthcare. She discusses the challenges facing primary care providers, the role of genetic testing in personalized medicine, and how Biography Health is working to empower both patients and doctors....

Gen Z Takes Action: The Preventive Health Shift In this episode, we're joined by two younger guests for our Gen Z special featuring Eliana Stanford, Dr. Stanford's daughter, and Lexie Horizon, whose parents are fellow doctors and friends of Dr. Stanford, and who recently interned at Biography Health. This unique conversation explores why younger generations should care about and take action towards preventive healthcare. Timestamps: 03:39:19 - Elena and Lexie introduce themselves and their...

Taylor Can't Outrun His Genetics: Lipid Panel Reality Check In this episode, Dr. Stanford and I uncover surprising truths from my advanced lipid panel. Despite my active lifestyle, the results reveal hidden risks for heart disease and diabetes. We explore how genetic factors and subtle imbalances can impact long-term health, and discuss targeted interventions that could make all the difference.  Timestamps: 00:02:39 - Overview of advanced lipid panel and family history  00:05:16 - Discussion...

In this informative episode of the Precision Medicine Made Simple Podcast, we delve into the world of lipids with Dr. Stanford. Learn what lipids are and why they're crucial for your health, especially regarding heart disease prevention. We explore the differences between HDL and LDL cholesterol, discuss genetic factors influencing lipid levels, and explain why even vegetarians need to pay attention to their lipid profiles. Dr. Stanford breaks down advanced lipid panels, explaining key...

From Genes to Actions: Taylor's DNAbled Blueprint Experience Today marks the beginning of an ongoing series where I'm pulling back the curtain on my personal journey through the DNAbled Blueprint process. You'll get an exclusive, firsthand look at: My own intake form: Revealing insights from my personal and family health historyOne of my genetic reports: Dr. Stanford examines my polygenic risk score, discussing my genetic predisposition to certain health conditionsMy personalized DNAbled...

Cracked the Genetic Code! Methylation and the Future of Precision Medicine This is the second half of the two part series to Dr. Stanford’s presentation called, “Optimizing Healthspan and Longevity by Implementing Personalized Precision Medicine.” For this episode, we dive into the science of methylation patterns and how we can use it to detect various cancers and their tissue origins enabling early intervention for better treatment outcomes and ultimately paving the way for tailored...

These next two episodes are a two part series to Dr. Stanford’s presentation called “Optimizing Healthspan and Longevity by Implementing Personalized Precision Medicine. Think of this episode like Precision Medicine 101. Dr. Stanford dives into a number of different topics including the evolution of personalized precision medicine and how its changing healthcare, the significance of knowing your risks by looking at genetics, family history, monogenic risks and polygenic risk scores, and...

For this episode, Dr. Stanford, Alyssa Stanford, and Taylor Cu discuss the topic of cancer. Dr. Stanford provides a comprehensive breakdown of cancer cells, stressing the need for genetic and molecular profiling to tailor treatments. They explore the factors that contribute to cancer development, including lifestyle choices and genetic mutations, and emphasize the importance of early detection through screenings and genetic analysis. They also dive into the exciting advancements in early...

For this episode, Dr. Stanford, Alyssa Stanford, and Taylor Cu dive into the complexities of metabolic syndrome, how it can relate to several chronic diseases and discuss the impact of genetics, diet, and exercise on our overall health. We also touch on the importance of precision medicine and continuous glucose monitoring in managing conditions like diabetes and touch on some of the benefits of medications currently out there like Ozempic. Timestamps: [00:05:44] Metabolic syndrome increases...

In this episode, we’re joined by Dr. Stanford and Taylor Cu to explore neurodegenerative diseases such as Alzheimer’s and Parkinson's. It's a particularly personal discussion as Dr. Stanford shares his own genetic risk for Alzheimer’s, linked to the APOE4 gene. Dr. Stanford explains what neurodegenerative diseases are and dives into the specifics of Alzheimer's, including how genetics play a role in its risk. We wrap up the episode by looking at lifestyle changes that could make a significant...

Dr. Stanford, Alyssa Stanford, and Taylor Cu explore the fascinating world of heart disease and personalized health care. They dive into the complexities of heart disease, discussing the crucial role of genetics, family history, lifestyle, and biochemistry in assessing heart disease risk. Tune in to discover the power of early detection, personalized health plans, and integrative approaches to effectively address heart disease and more. Timestamps: [00:05:14] Arterial hardening and narrowing...