In this episode, Dr. Yelena Bykhovskaya, Chief Scientific Officer at Biography Health, shares her expertise in genetics. We explore the importance of both polygenic and monogenic risk scores in patient care. The conversation underscores the value of combining cutting-edge genetic analysis with traditional clinical factors in the evolving field of precision medicine, emphasizing the need for a comprehensive approach to patient care. Resources Mentioned: https://www.genomeweb.com/ https://www.insideprecisionmedicine.com/ Timestamps: 00:03:34 - LinkedIn sparks Bykhovskaya-Stanford collaboration 00:06:27 - Stanford highlights Bykhovskaya's genetic risk expertise 00:13:13 - Genetic risk vs. family history explained 00:18:18 - Human Genome Project revolutionizes genetic analysis 00:24:54 - Whole genome sequencing: Key to comprehensive risk assessment 00:28:49 - High polygenic scores rival monogenic variants in risk 00:33:33 - Early intervention: Combating genetic predispositions 00:38:09 - Integrated risk scores: Combining genetics and clinical factors 00:44:00 - Basic genetic knowledge empowers doctors 00:52:59 - Addressing European bias in genetic studies Dr. William Stanford MD PHD FACP Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians. A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist. Since 2018, he has provided genomic and precision medicine consultations through the Beverly Hills Sponsored by: Biography Health Biography Health, where healthcare meets personalization. With their DNAbled™ Blueprint, Biography Health empowers you with a health plan based on your unique DNA, aiming to prevent disease and extend your life. Take control of your health journey with a plan as unique as you. Visit BiographyHealth.com and start your personalized healthcare journey today.