Episodes
Dr. Alice Long is an Associate Member of the Center for Translational Immunology at Benaroya Research Institute at Virginia Mason. The Long lab is focused on understanding how tolerance is lost in autoimmunity, specifically as it related to type 1 diabetes. Dr. Long discusses the work she presented at the American Association of Immunologists’ annual meeting, IMMUNOLOGY2022, on CD8 T cell exhaustion and Treg modulation.
Published 05/10/22
Published 05/10/22
Dr. Shruti Naik is an Assistant Professor of Biological Sciences at New York University Langone Medical Center. She studies immunity in the epithelial tissues that line our body to understand how environmental stimuli collaborate with genetic factors to influence health and drive disease at these interfaces. She discusses the work she's presenting at the American Association of Immunologists' annual meeting, IMMUNOLOGY2022, on trained immunity and immune-epithelial crosstalk in tissue repair.
Published 05/08/22
Dr. Gwendalyn Randolph is the Emil R. Unanue Distinguished Professor in the Department of Immunology and Pathology at Washington University in St. Louis. Research in her lab integrates the study of monocytes, monocyte-derived cells, and dendritic cells with vascular and lymphatic vessel biology. She discusses the work she's presenting at the American Association of Immunologists' annual meeting, IMMUNOLOGY2022, on the diversity, function, and mysteries of peritoneal macrophages. 
Published 05/06/22
Dr. Michael Rosenblum is a Professor of Dermatology at the University of California, San Francisco. His lab seeks to to understand how immune responses are regulated in tissues and how this knowledge can be exploited for therapeutic benefit. They are currently investigating how Tregs control immune responses in tissues, as well as their “alternative” functions. He talks about early-life inflammation and type 2 helper T cells in the skin, and how Tregs can be manipulated to target autoimmune...
Published 04/26/22
Dr. Gary Koretzky is President of the American Association of Immunologists, Vice Provost for Academic Integration at Cornell University, Professor of Medicine at Weill Cornell Medicine, and Director of the Cornell Center for Immunology. He talks about how he began his career in immunology, using science to guide Cornell's response to COVID-19, and what to expect at AAI's Immunology 2022 meeting taking place May 6-10th.
Published 04/12/22
Dr. Florian Krammer is a Professor of Vaccinology at Icahn School of Medicine at Mount Sinai. His lab focuses on understanding broadly-reactive immune responses against the surface glycoproteins of RNA viruses such as influenza, with the goal to develop better vaccines and novel therapeutics. He talks about his lab's shift to COVID-19 research, strategies for vaccine development, and how we can prepare for future pandemics.
Published 03/29/22
Dr. Andy Kokaji is a Senior Director of Immunology, and Dr. Hannah Lee is a Senior Director of Product Management, at STEMCELL Technologies. They discuss their career paths and how they develop and commercialize products to support scientists worldwide.
Published 03/15/22
Dr. Jennifer Gommerman is a Professor of Immunology at the University of Toronto. Her team has uncovered a novel gut-brain axis that regulates neuroinflammation and is examining the role of B lymphocytes in Multiple Sclerosis (MS) patients and in animal models of MS. More recently, she has been studying the antibody response to SARS-CoV-2 in saliva samples from patients with COVID-19. She talks about the role of gut-derived plasma cells in multiple sclerosis, and how salivary immunoglobulin A...
Published 03/01/22
Dr. Caetano Reis e Sousa is the Assistant Research Director and Senior Group Leader at the Francis Crick Institute. His lab studies the molecular pathways that trigger dendritic cells into action. He talks about the mechanisms of dendritic cell cross-presentation, RNA interference, and dendritic cell progenitors in influenza.
Published 02/15/22
Dr. Francesco Colucci is a Wellcome Investigator and Professor of Immunology at the University of Cambridge. His research focuses on natural killer (NK) and other innate lymphoid cells, as well as immunogenetics. He talks about uterine NK cells and their education, and falling in love with research as a physician.
Published 02/01/22
Dr. Mihai Netea is a Professor of Experimental Medicine at Radboud University Nijmegen and a Professor of Immunometabolism at the University of Bonn. He discusses the mechanisms of trained immunity, transmission of immune traits across generations via epigenetics, and how some vaccines can enhance immunity to other pathogens.
Published 01/18/22
Dr. De’Broski Herbert is an Associate Professor of Immunology at the University of Pennsylvania. The Herbert lab is exploring the immunoregulatory and regenerative mechanisms operating at the mucosal interface. He discusses his recent paper on IL-33 sources and secretion, his postdoctoral fellowship in South Africa, and the M1/M2 macrophage paradigm.
Published 12/21/21
Dr. Keke Fairfax is an Associate Professor of Microbiology and Immunology and the Director of Equity, Diversity, and Inclusion at the University of Utah.  Her lab uses helminth parasite Schistosoma mansoni as a tool to understand the consequences of IL-4 induced immuno-modulation.  She explains how helminth infections can reduce the efficacy of childhood vaccinations, and how mentorship and networking can help minority scientists thrive in Utah.
Published 12/07/21
Dr. Tri Phan is a Senior Research Fellow at the Garvan Institute of Medical Research and a Conjoint Professor at the University of New South Wales. He runs the Intravital Microscopy Lab, which aims to understand the checks and balances that control B cell responses. His team uses two-photon microscopy to image cells in live animals, including time-lapses of over 24 hours. He talks about the physics behind this type of microscopy and how it can image deep within tissues without destroying...
Published 11/23/21
Dr. Jenny Ting is the William R. Kenan Jr. Distinguished Professor of Genetics at the University of North Carolina at Chapel Hill, and served as the President of the American Association of Immunologists from 2020-2021. Her lab discovered the NLR protein family, and their recent research interests include oxidative phosphorylation in HIV, the role of AIM2 in autoimmunity, and microbes that can protect from radiation.
Published 11/09/21
Dr. Dario Vignali is the Frank Dixon Chair in Cancer Immunology and Vice Chair and Professor of Immunology at University of Pittsburgh School of Medicine.  His lab studies various aspects of T cell regulation, and recently generated a new mouse model to target conventional CD4 T cells.
Published 10/26/21
Dr. Anil Bhushan is a Professor at the University of California, San Francisco School of Medicine and Co-Founder of Deciduous Therapeutics, an aging therapeutics company developing a novel class of immune-modulatory therapies. His lab focuses on understanding how the immune system senses and tunes its response to senescent cells in disease and aging and was one of the first to show the role of clearing senescent cells in models of type 1 diabetes.
Published 10/12/21
Dr. Michael Burton is an Assistant Professor at the University of Texas in Dallas. His lab studies the complex interactions between the immune and nervous systems that lead to pain, depression, and sickness.
Published 09/28/21
Dr. Frances Lund is the Charles H. McCauley Professor and Chair of the Department of Microbiology at the University of Alabama at Birmingham. Her lab showed that B cells not only make antibodies, but also produce cytokines that modulate the microenvironment. She currently studies the many roles of B cells, how to target B cells gone bad, and nasal vaccines for respiratory illnesses.
Published 09/14/21
Dr. Jeffrey Bluestone is the CEO and President of Sonoma Biotherapeutics, a San Francisco and Seattle-based company leveraging the properties of regulatory T cells to create living cell therapies that restore the immune system back to its balanced, fully functioning state.
Published 08/31/21
Dr. Christopher Klebanoff is an Principal Investigator and Attending Physician at Memorial Sloan Kettering Cancer Center. His research focuses on cell-based cancer immunotherapies, T cell receptors, and the therapeutic targeting of shared cancer neoantigens. Using single-cell sequencing, biophysical measurements of T cell receptor affinity, genetic engineering, and structural immunobiology, the Klebanoff lab aims to adapt adoptive T cell transfer for advanced solid tumors.
Published 08/17/21
Dr. James Crowe is the Director of the Vanderbilt Vaccine Center. Their group uses a very broad array of techniques including molecular and cellular biology, state-of-the-art imaging and flow cytometry, bioinformatics, and bioengineering approaches to attack the scientific problems that are of interest to them: major human pathogens.
Published 08/03/21
Guest: Dr. Marc Jenkins is a Regents and Distinguished McKnight University Professor  in the Department of Microbiology and Immunology and the Director of the Center for Immunology at the University of Minnesota. Dr. Jenkins discovered…
Published 07/20/21
Dr. Robyn Hall is a Research Scientist and Team Leader at the Commonwealth Scientific and Industrial Research Organisation (CSIRO). She is a veterinary virologist whose research focuses on innovative and applied solutions for improving rabbit biocontrol using rabbit caliciviruses.
Published 07/06/21