In the first episode of "Whiskey High IQ," Brian Bailie introduces Four Roses Single Barrel and dives into whiskey basics, explaining it as a distilled spirit made from grains like barley, corn, rye, and wheat. He outlines the origins of whiskey in Ireland and Scotland, discusses the regional spelling differences ("whiskey" vs. "whisky"), and provides an overview of the four primary grains used in whiskey production. Barley is known for its rich, complex flavors and is key in Scotch and Irish whiskies. Corn, the main ingredient in bourbon, contributes sweetness and smoothness. Rye offers bold, spicy, and complex flavors, while wheat brings a mellow, smooth profile, often found in weeded bourbons. He encourages listeners to explore these grains through tasting various whiskeys to deepen their understanding and appreciation.