Digital transformation impacts many areas of our lives and has given rise to a booming digital economy. This new commodity of data is continually growing and changing. The challenge however, is how this digital transformation can be harnessed to do what we already do, but much better. Mathematics Applications Consortium for Science & Industry (MACSI) and Confirm, the SFI Research Centre for Smart Manufacturing hosted a panel of experts to tackle the topic: Chris Decubber, Technical Director at the European Factories of the Future Research Association (EFFRA), Dr Johan S Carlson, Director of the Fraunhofer-Chalmers Research Centre for Industrial Mathematics, Dr Joanna Jordan, Institute for Mathematical Innovation, University of Bath, Professor Barry O'Sullivan, Director of Insight the SFI Centre for Data Analytics, Prof James Gleeson, Co-Director of MACSI.