Despite not having a known function, cellular “vaults” are on the verge of being harnessed for all kinds of applications, and looking at the evolution of brown fat into a heat-generating organ   First on this week’s show, Managing News Editor John Travis joins host Sarah Crespi to discuss mysterious cellular complexes called “vaults.” First discovered in the 1980s, scientists have yet to uncover the function of these large, common, hollow structures. But now some researchers are looking to...

Studying color vision in with children who gain sight later in life, joining a cancer trial doesn’t improve survival odds, and the first in our books series this year First on this week’s show, Staff Writer Jennifer Couzin-Frankel joins host Sarah Crespi to discuss the pros and cons of participating in clinical trials. Her story challenges the common thinking that participating in a trial is beneficial—even in the placebo group—for cancer patients.   Next, Lukas Vogelsang, a postdoctoral...

A roundup of online news stories featuring animals, and researchers get crows to “count” to four   This week’s show is all animals all the time. First, Online News Editor Dave Grimm joins host Sarah Crespi to discuss stepping on venomous snakes for science, hunting ice age cave bears, and demolishing lizardlike buildings.   Next, producer Kevin McLean talks with Diana Liao, a postdoctoral researcher at the University of Tübingen, about teaching crows to count out loud. They discuss the...

On this week’s show: What happens when the body’s own immune system attacks the brain, and how otters’ use of tools expands their diet   First on the show this week, when rogue antibodies attack the brain, patients can show bizarre symptoms—from extreme thirst, to sleep deprivation, to outright psychosis. Contributing Correspondent Richard Stone joins host Sarah Crespi to discuss the hunt for biomarkers and treatments for this cluster of autoimmune disorders that were once mistaken for...

Jupiter’s moon Io has likely been volcanically active since the start of the Solar System, and a proposal to safeguard healthy human subjects in clinical trials First on the show this week, a look at proposed protections for healthy human subjects, particularly in phase 1 clinical trials. Deputy News Editor Martin Enserink joins host Sarah Crespi to discuss the risks healthy participants face when involved in early testing of drugs for safety and tolerance. Then, we hear about a project to...

Bringing historical seismic reports and modern seismic risk maps into alignment, and a roundup of stories from our newsletter, ScienceAdviser   First on the show this week, a roundup of stories with our newsletter editor, Christie Wilcox. Wilcox talks with host Sarah Crespi about the oldest ice ever found, how well conservation efforts seem to be working, and repelling mosquitoes with our skin microbes.   Next on this episode, evaluating seismic hazard maps. In a Science Advances paper this...

Researchers try to identify effective loneliness interventions, making the Sandmeyer safer, and books that look to the future and don’t see doom and gloom   First up on the show, Deputy News Editor Kelly Servick explores the science of loneliness. Is loneliness on the rise or just our awareness of it? How do we deal with the stigma of being lonely?   Also appearing in this segment: ●     Laura Coll-Planas ●     Julianne Holt-Lunstad ●     Samia Akhter-Khan   Next, producer Ariana Remmel talks...

A different source of global warming, signs of a continentwide tradition of human sacrifice, and a virus that attacks the cholera bacteria   First up on the show this week, clearer skies might be accelerating global warming. Staff Writer Paul Voosen joins host Sarah Crespi to discuss how as air pollution is cleaned up, climate models need to consider the decrease in the planet’s reflectivity. Less reflectivity means Earth is absorbing more energy from the Sun and increased temps.   Also from...

]Researchers are testing HIV drugs and monoclonal antibodies against long-lasting COVID-19, and what it takes to turn a symbiotic friend into an organelle   First up on the show this week, clinical trials of new and old treatments for Long Covid. Producer Meagan Cantwell is joined by Staff Writer Jennifer Couzin-Frankel and some of her sources to discuss the difficulties of studying and treating this debilitating disease.   People in this segment: ·      Michael Peluso ·      Sara...

Tracing the arrival of rats using bones, isotopes, and a few shipwrecks; and what scientists have learned in 50 years about our famous ancestor Lucy   First on the show: Did rats come over with Christopher Columbus? It turns out, European colonists weren’t alone on their ships when they came to the Americas—they also brought black and brown rats to uninfested shores. Eric Guiry, a researcher in the Trent Environmental Archaeology Lab at Trent University, joins host Sarah Crespi to discuss how...

Robots that can smile in synchrony with people, and what ends up in the letters section First on this week’s show, a robot that can predict your smile. Hod Lipson, a roboticist and professor at Columbia University, joins host Sarah Crespi to discuss how mirrors can help robots learn to make facial expressions and eventually improve robot nonverbal communication.   Next, we have Margaret Handley, a professor in the department of epidemiology and biostatistics and medicine at the University of...

New clinical trials for treatments of an always fatal brain disease, and what happens with pests when a conventional and organic farm are neighbors   First up on this week’s show, a new treatment to stave off prion disease goes into clinical trials. Prions are misfolded proteins that clump together and chew holes in the brain. The misfolding can be switched on in a number of ways—including infection with a misfolded prion protein from an animal or person. Staff Writer Meredith Wadman talks...

Investigating “infantile amnesia,” and how generalized fear after acute stress reflects changes in the brain   This week we have two neuroscience stories. First up, freelance science journalist Sara Reardon looks at why infants’ memories fade. She joins host Sarah Crespi to discuss ongoing experiments that aim to determine when the forgetting stops and why it happens in the first place.   Next on the show, Hui-Quan Li, a senior scientist at Neurocrine Biosciences, talks with Sarah about how...

What modern Indian genomes say about the region’s deep past, and how vitamin A influences stem cell plasticity First up this week, Online News Editor Michael Price and host Sarah Crespi talk about a large genome sequencing project in India that reveals past migrations in the region and a unique intermixing with Neanderthals in ancient times.   Next on the show, producer Kevin McLean chats with Matthew Tierney, a postdoctoral fellow at Rockefeller University, about how vitamin A and stem cells...

Keeping water out of the stratosphere could be a low-risk geoengineering approach, and using magnets to drive medical robots inside the body   First up this week, a new approach to slowing climate change: dehydrating the stratosphere. Staff Writer Paul Voosen joins host Sarah Crespi to discuss the risks and advantages of this geoengineering technique.   Next on the show, Science Robotics Editor Amos Matsiko gives a run-down of papers in a special series on magnetic robots in medicine. Matsiko...

On this week’s show: Factors that pushed snakes to evolve so many different habitats and lifestyles, and news from the AAAS annual meeting   First up on the show this week, news from this year’s annual meeting of AAAS (publisher of Science) in Denver. News intern Sean Cummings talks with Danielle Wood, director of the Space Enabled Research Group at the Massachusetts Institute of Technology, about the sustainable use of orbital space or how space exploration and research can benefit...

Why squeezing a blueberry doesn’t get you blue juice, and a myth buster and a science editor walk into a bar   First up on the show this week, MythBusters’s Adam Savage chats with Science Editor-in-Chief Holden Thorp about the state of scholarly publishing, better ways to communicate science, plus a few myths Savage still wants to tackle.   Next on the show, making blueberries without blue pigments. Rox Middleton, a postdoctoral fellow at the Dresden University of Technology and honorary...

More than 200 materials could be “altermagnets,” and the impact of odiferous pollutants on nocturnal plant-pollinator interactions   First up on the show this week, researchers investigate a new kind of magnetism. Freelance science journalist Zack Savitsky joins host Sarah Crespi to talk about recent evidence for “altermagnetism” in nature, which could enable new types of electronics.   Next on the show, producer Meagan Cantwell talks with Jeremy Chan, a postdoctoral researcher at the...

A remote island may hold clues for the future of El Niño and La Niña under climate change, and how pressure in the blood sends messages to neurons   First up, researchers are digging into thousands of years of coral to chart El Niño’s behavior over time. Producer Kevin McLean talks with Staff Writer Paul Voosen about his travels to the Pacific island of Vanuatu to witness the arduous task of reef drilling.   Next on the show, host Sarah Crespi talks with Veronica Egger, a professor of...

On this week’s show: A roundup of stories from our daily newsletter, and the ripple effects of the invasive big-headed ant in Kenya First up on the show, Science Newsletter Editor Christie Wilcox joins host Sarah Crespi to talk about snake venom antidotes, a surprising job for a hangover enzyme, and crustaceans that spin silk.   Next on the show, the cascading effects of an invading ant. Douglas Kamaru, a Ph.D. student in the Department of Zoology & Physiology at the University of...

Investigation shows journal editors getting paid to publish bunk papers, and new techniques for finding tumor DNA in the blood   First up on this week’s episode, Frederik Joelving, an editor and reporter for the site Retraction Watch, talks with host Sarah Crespi about paper mills—organizations that sell authorship on research papers—that appear to be bribing journal editors to publish bogus articles. They talk about the drivers behind this activity and what publishers can do to stop...

Assessing environmental damage during wartime, and tracking signaling between fetus and mother   First up, freelance journalist Richard Stone returns with news from his latest trip to Ukraine. This week, he shares stories with host Sarah Crespi about environmental damage from the war, particularly the grave consequences of the Kakhovka Dam explosion.   Next, producer Kevin McLean talks with researcher Nardhy Gomez-Lopez, a professor in the department of obstetrics and gynecology and pathology...

Best of online news, and screening for tuberculosis using sound   This week’s episode starts out with a look back at the top 10 online news stories with Online News Editor David Grimm. There will be cat expressions and mad scientists, but also electric cement and mind reading. Read all top 10 here.   Next on the show, can a machine distinguish a tuberculosis cough from other kinds of coughs? Manuja Sharma, who was a Ph.D. student in the department of electrical and computer engineering at the...

Seeking the Majorana fermion particle, and a look at El Salvador’s adoption of cryptocurrency   First up on the show this week, freelance science journalist Zack Savitsky and host Sarah Crespi discuss the hunt for the elusive Majorana fermion particle, and why so many think it might be the best bet for a functional quantum computer. We also hear the mysterious tale of the disappearance of the particle’s namesake, Italian physicist Ettore Majorana.   Next in the episode, what happens when you...

Top science from 2023, and a genetic tool for pangolin conservation   First up this week, it’s Science’s Breakthrough of the Year with producer Meagan Cantwell and News Editor Greg Miller. But before they get to the tippy-top science find, a few of this year’s runners-up. See all our end-of-year coverage here.   Next, Jen Tinsman, a forensic wildlife biologist at the U.S. Fish and Wildlife Service, joins host Sarah Crespi to discuss using genetics to track the illegal pangolin trade. These...