In this episode we discuss: Whether you should be concerned about high LDL or high cholesterol on a low-carb diet The validity of the Lean Mass Hyper-Responder (LMHR) Phenotype and Lipid Energy Model proposed by Dave Feldman The metabolic state that drives the Lipid Energy Model How the "Lean Mass Hyper-Responder" and Lipid Energy Model support the Bioenergetic view of cardiovascular disease   Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide   Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/   Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/   The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/   Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-115-lmhr-and-the-lipid-energy-model-implications-for-metabolism-and-hormones   Timestamps: 0:00 – intro 1:14 – what is the Lean Mass Hyper-Responder (LMHR) phenotype 3:33 – how the Lipid Energy Model challenges the mainstream dogmatic view linking high cholesterol levels to heart disease 6:33 – the protective effects of cholesterol and why it does not cause heart disease, despite being necessary for atherosclerosis 9:49 – the distinction between Lean Mass Hyper-Responders and those with high cholesterol levels in the context of metabolic dysfunction 15:10 – what is the Lipid Energy Model 22:10 – how the body adapts to a lack of carbohydrates, leading to elevated cholesterol levels 27:22 – the hormonal and metabolic state underlying the Lean Mass Hyper-Responder phenotype 32:21 – how adding carbohydrates lowers cholesterol levels in those who don't have metabolic dysfunction at a cellular level 37:11 – whether Lean Mass Hyper-Responders are at increased risk of cardiovascular disease 42:00 – why the Lean Mass Hyper-Responder phenotype isn't ideal: stress and low thyroid function 51:10 – the parallels between the lipid energy model and physiological insulin resistance