The following is a conversation with Dr Saman Maleki, associate professor at Western University with a special focus on oncology, immuno oncology, microbiology, and everything to do with the immune system and the microbiome. Dr Maleki is a pioneer and a world leader in the field of sensitising tumours to immunotherapy through modulating the microbiome. During this conversation, we talked about the state of the art associated with the microbiome and cancer. So if you're interested in how cancer impacts the microbiome and how the microbiome impacts cancer you should listen to this episode. We delved into what the latest evidence is for the use of FMT in making a particular type of cancer therapy called immunotherapy better for treating particular cancers. We talked about the journey from doing the first trials to the area where they are now, which is raising funds to do much larger trials that should definitively prove that changing the microbiome can massively improve response rates to cancer therapies. Even as someone who's got their finger on the pulse of this field, I left the conversation enthusiastic and excited about the potential in the future for developing efficient microbiome treatments to tackle cancer. 00:00:00 Introduction 00:01:38 First interest in the microbiome 00:05:46 FMT for C-Diff patients 00:09:11 Using the immune system to treat cancer 00:19:03 Microbiome research for oncology 00:23:46 Journey from first study 00:27:30 Stimulating immune system with FMT 00:39:09 Chemotherapy, pancreatic cancer and the microbiome 00:48:29 Novel cell therapy and chemotherapy 00:49:02 Future of immunotherapy 00:52:32 Immune therapy response in cancer treatment 00:55:41 Antibiotics and cancer treatment