En este nuevo episodio intento analizar una pregunta clásica, ¿Qué es mejor los sueros balanceados o el suero salino para el paciente crítico? Para ello, me basaré en el articulo publicado en marzo de 2022 en la New England Journal of Medicine “Solución multielectrolito equilibrada frente a salina en adultos gravemente enfermos” La bibliografía utilizada para el episodio: Finfer, S., Micallef, S., Hammond, N., Navarra, L., Bellomo, R., Billot, L., Delaney, A., Gallagher, M., Gattas, D., Li, Q., Mackle, D., Mysore, J., Saxena, M., Taylor, C., Young, P., Myburgh, J., PLUS Study Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group, & PLUS Study Investigators and Australian New Zealand Intensive Care Society Clinical Trials Group (2022). Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults. The New England journal of medicine, 386(9), 815–826. https://doi.org/10.1056/NEJMoa2114464 Zampieri FG, Machado FR, Biondi RS, et al. Effect of intravenous fluid treatment with a balanced solution vs 0.9% saline solution on mortality in critically ill patients: the BaSICS randomized clinical trial. JAMA 2021;326:818-829. Hammond NE, Zampieri FG, Di Tanna GL, et al. Balanced crystalloids versus saline in critically ill adults — a systematic review with meta-analysis. NEJM Evid 2022;1(2). DOI: 10.1056/EVIDoa2100010. Ramanan M, Attokaran A, Murray L, et al. Sodium chloride or Plasmalyte-148 evaluation in severe diabetic ketoacidosis (SCOPE-DKA): a cluster, crossover, randomized, controlled trial. Intensive Care Med 2021;47:1248-1257. Self WH, Evans CS, Jenkins CA, et al. Clinical effects of balanced crystalloids vs saline in adults with diabetic ketoacidosis: a subgroup analysis of cluster randomized clinical trials. JAMA Netw Open 2020;3(11):e2024596-e2024596.