In this first in a series of podcasts looking back at the best abstracts from the 2023 ACRO Annual Meeting, Dr. Jessica Schuster interviews two of our talented contributors regarding their research projects. Dr. Clair Lanier from Wake Forest discusses her project entitled: Examining the Impact of Tumor Bulk in Patients with Diffuse Large B-Cell Lymphoma Treated with Chemo Alone: A Secondary Analysis of a Prospective Randomized Trial. Followed by a dynamic discussion with Dr. Asona Lui, from UC San Diego, regarding her research project: ReIGNITE RT Boost: Interim Analysis of an International Study Testing the Feasibility and Accuracy of using Restriction Spectrum Imaging (RSI) MRI to Guide Prostate Cancer Target Volume for Radiotherapy Boost.