Approximately four in 10 Americans are obese, putting millions at increased risk of developing diabetes, heart disease, liver cancer, and other chronic illnesses. For many years it’s seemed that we’re losing the battle against this modern epidemic. However, the tide may be turning with the recent approval of a revelatory new class of medications. In today’s episode, Dan and Derek dive deep into this new type of treatments. They discuss their discovery, the biology behind them, the pivotal clinical trials showing their efficacy, and the promises and perils of this powerful new tool in the fight against obesity. Wilding et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. The New England Journal of Medicine, March 2021. DOI: 10.1056/NEJMoa2032183 The information presented here is not medical advice. Consult your physician for any questions regarding your personal health.