In this Big Compute Podcast episode, Gabriel Broner hosts Dave Turek, Vice President of HPC and Cognitive Systems at IBM, to discuss how AI enables the acceleration of HPC workflows. HPC has traditionally relied on simulation to represent the real world. Over the last several years AI has had significant growth due to innovation, growth in compute capacity, and new architectures that have enabled it. HPC can benefit from AI techniques. One area of opportunity is to augment what people do in preparing simulations, analyzing results and deciding what simulation to run next. Another opportunity exists when we take a step back and analyze whether we can use AI techniques instead of simulations to solve the problem. We should think about AI as increasing the toolbox HPC users have. We should learn about them and incorporate them, as in the future the separation between HPC and AI may simply not exist.