Continuing education episode! Every now and then, when a transfusion service does a pretransfusion workup, they find that the patient's plasma is incompatible with EVERY other red cell! In other words, NOTHING is compatible! These situations are intimidating, and can lead to delays in transfusion. Dr. Jill Storry is an international immunohematology expert, and she shares practical tips for what to do and how to recognize the three main patterns of panagglutinins.