A Diabetes Breakthrough: New Drug to Delay the Onset of Clinical Disease
Listen now
Description
Welcome back to another exciting season of Charting Pediatrics! For our long-time listeners, we are thrilled to have you back, and for anyone new to our audience, we couldn’t be more excited that you’ve joined us. In this first episode of Season 7, we dive into the world of Type 1 diabetes (T1D). Did you know that one in 300 individuals under the age of 20 is affected by this condition? Our guest on today’s episode, Kimber Simmons, MD, isn’t just an expert in her field; she was a part of that statistic after getting diagnosed at just 8 –years old. Now, as an associate professor of pediatrics and pediatric endocrinology, as well as a pediatric endocrinologist at Children’s Hospital Colorado and the Barbara Davis Center for Diabetes, she’s shedding light on some of the latest research.  Dr. Simmons and other experts explain alternative approaches that modify the natural course of T1D, rather than solely treating hyperglycemia, could dramatically improve both the quality of life and health outcomes for patients. In this episode, we review strategies for early diagnosis of T1D that predict, as well as prevent or delay, the onset of clinical T1D during preclinical stages of the disease. We also discuss an exciting new medication, Tzield (teplizumab-mzwv), with the promise of delaying the onset of clinical disease in T1D. “It is going to shift how we manage Type 1 diabetes in the future,” Dr. Simmons says.   Some highlights from today’s episode include:  How the predictability of T1D has changed over the years  Expansion of screening programs worldwide  New breakthrough medication, Tzield (teplizumab-mzwv), approved in the U.S. to delay the onset of clinical T1D  Children’s Colorado program to help providers identify the disease and follow up  For more information on Children’s Hospital Colorado, visit: childrenscolorado.org 
More Episodes
  Earlier this year, new guidelines were released to improve the diagnosis of pediatric sepsis and septic shock. For the first time, the novel Phoenix Sepsis Criteria provides an objective and data-driven approach to aid in the identification of these life-threatening conditions, including...
Published 06/25/24
Published 06/25/24
Newborn screening has expanded dramatically over the last decade as our detection methods improved and new treatments became available for rare diseases. One of those rare diseases is adrenoleukodystrophy, otherwise known as ALD. ALD is an example of a rare disease where, thanks to expansions in...
Published 06/18/24