If you experience any technical difficulties with this video or would like to make an accessibility-related request, please send a message to [email protected]. The growing torrent of information released by city governments and collected by researchers is connecting with new tools developed by computer scientists, enabling significant advances in urban planning, medicine, social science and other spheres. On November 20, 2013 representatives of those fields gathered onstage for Chicago: City of Big Data, a UChicago Discovery Series panel discussion of research and educational efforts focused on transforming cities through data and computation. In a vibrant 90-minute conversation moderated by Charlie Catlett, director of the Urban Center for Computation and Data (UrbanCCD), the panelists described work underway at the University of Chicago and Argonne National Laboratory and outlined their visions for the future of data-driven urban design and governance.