Please visit answersincme.com/YUM860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in ophthalmology discusses strategies for better referral and treatment for patients with diabetic retinopathy and diabetic macular edema. Upon completion of this activity, participants should be better able to: Recognize the clinical rationale for timely patient referral to ophthalmologic specialists for an evaluation of diabetic retinopathy (DR) and diabetic macular edema (DME) in appropriate patients; Outline strategies for use in primary care to enhance outcomes for patients who are at risk of, or who have developed, DR and DME; and Review the clinical impact of available vascular endothelial growth factor (VEGF)-targeted agents for use in DR and DME.