Dennis Cleary discusses with Monica Robinson how opioid-use disorder is a national population health crisis affecting those of all ages. Understanding the demographic, socioeconomic, psychosocial, and substance use characteristics of different groups of opioid users allows OT practitioners to tailor interventions. OT practitioners can provide interventions across the life span supporting a return to meaningful occupations, roles, and routines. This is part of the Continued Learning Podcast series.