We often think of dry eye disease (DED) as merely an ocular disorder. But what about the systemic conditions that might dictate the terms of DED? In the debut episode of the miniseries “International Perspectives on Dry Eye Disease,” Laura Periman, MD (United States), invites Mile Brujic, OD (United States), and Victor Perez, MD (United States), to discuss how often-overlooked systemic disorders may actually be driving or exacerbating DED in some patients.  This editorially independent podcast is supported with advertising by Novartis.