Single-cell sequencing is a technology that is giving us new genomic capabilities. Dr. Luciano Martelotto joins us to explain how single-cell sequencing allows scientists to understand cells as building blocks, much like LEGO™, which form part of a much bigger structure such as an organ, a tissue, a disease, and so forth. Dr. James McLaren utilizes this technology to look at septicemia; in his work he is using single-cell analysis to better understand sepsis and to develop a rapid diagnostic test. Single-cell sequencing could hold the key to understanding why the body reacts to infections, and overall to help us advance healthcare. Join Dodi, Conor and their guests, Dr. Luciano Martelotto, Scientific Director of Single Cell Lab at Harvard Medical School, and Dr. James McLaren, Systems Immunity lecturer at Cardiff University, in the latest episode of Discovery Matters.