In this episode, the discussants examines the following questions, raised after a Journal of Hepatology’s nomenclature article: Is the introduction of metabolic risk factors (MRF) for the definition of MASLD justified?What are the main issues regarding the measurement and thresholds for MRFs?Is the introduction of the MetALD category clinically justified?Is it necessary to worry about MRFs in a patient drinking increased or excessive amounts of alcohol and if yes, how should these be...

This EASL Studio episode covers the highlights of the SLD Summit 2023, including: Physiopathological mechanismProblems encountered in the cirrhotic stage in SLDNovelties about liver biopsiesFaculty Sven Francque (Moderator)Quentin Anstee (Faculty)Frank Tacke (Faculty)Maja Thiele (Faculty)Related episodes EASL Studio S5E2: Are 30% of the global population sick? A critical view on Steatotic Liver Disease and care pathwaysEASL Studio Live from EASL Congress 2023: Steatotic liver disease global...

Hepatitis E is an inflammation of the liver caused by infection with the hepatitis E virus (HEV). HEV infections are among the most common causes of acute hepatitis worldwide. 2 different settings: HEV genotypes 1 and 2 cause primarily in water-born outbreaks inn resource-limited settingsHEV genotypes 3 and 4 have emerged as porcine zoonoses in middle and high-income areas, including EuropeThis Studio focuses on Zoonotic Hep E, especially HEV Genotype 3 infection and discusses recent...

Thirty percent of the global population have too much fat in their liver. The big question is: are they really sick when most will not end up with liver disease? This episode discusses: How should they be assessed and by whom?What does this mean to healthcare systems?Are there downsides to systematic screening?Faculty Aleksander Krag (Moderator)Alina Allen (Faculty)Manal El-Sayed (Faculty)Ian Rowe (FacultyRelated episode EASL Studio Live from EASL Congress 2023: Steatotic liver disease global...

This #EASLStudio JHEP Live discusses the newly released EASL Clinical Practice Guidelines on Acute-on-chronic liver failure (ACLF). In particular: ICU admission criteria for patients with ACLFTreatment of infection and antibiotic selectionLiver supportLiver transplantation for ACLF: Sarcopenia and frailtyFaculty Richard Moreau (Moderator)Rajiv Jalan (Faculty)Constantine Karvellas (Faculty)Rakhi Maiwall (Faculty)All EASL Studio Podcasts are available on EASL Campus.

This EASL Studio Midday Talks was live broadcast during the EASL Congress 2023 and is presenting the work of international liver societies to beat liver diseases. Faculty Thomas Berg, EASL (Moderator)Marcelo Silva, ALEH (Faculty)Norah Terrault, AASLD (Faculty)Manal El-Sayed, SOLDA (Faculty)Shiina Shuichiro, APASL (Faculty)All EASL Studio Podcasts are available on EASL Campus.

This EASL Studio Closing was live broadcast during the EASL Congress 2023 and discusses the future of hepatology. Faculty Thomas Berg (Moderator)Aleksander Krag (Moderator)Tobias Böttler (Faculty)Debbie Shawcross (Faculty)All EASL Studio Podcasts are available on EASL Campus.

This EASL Studio Good Morning Vienna was live broadcast during the EASL Congress 2023 and is presenting the highlights of liver cancer research at the congress. Faculty Jean-Charles Nault (Moderator)Josep Llovet (Moderator)Jessica Zucman-Rossi (Faculty)Bruno Sangro (Faculty)Matthias Pinter (Faculty)All EASL Studio Podcasts are available on EASL Campus.

This EASL Studio Midday Talks was live broadcast during the EASL Congress 2023 and is covering practice changing following data presented during the congress. Faculty Virginia Hernández-Gea (Moderator)Ahmed Elsharkawy (Moderator)Maru Rinella (Faculty)Maria Reig (Faculty)Nancy Reau (Faculty)Verena Keitel (Faculty)All EASL Studio Podcasts are available on EASL Campus.

This EASL Studio Midday Talks was live broadcast during the EASL Congress 2023 and discusses the nomenclature change for steatotic liver disease. Faculty Aleksander Krag, EASL (Moderator)Philip Newsome, EASL (Faculty)Maru Rinella, AASLD (Faculty)Graciela Castro-Narro, ALEH (Faculty)Mohamed El-Kassas, SOLDA (Faculty)Robert Mitchell-Thain, LPI (Faculty)Lorraine Stiehl, ALF (Faculty)All EASL Studio Podcasts are available on EASL Campus.

This EASL Studio Midday Talks was live broadcast during the EASL Congress 2023 and discusses the newly released EASL policy statement on alcohol harm and related liver diseases. The document aims to highlight the extensive harm resulting from alcohol consumption and shine a light on the effective, yet underused, harm reduction policies available to European countries. Faculty Frank Murray Ireland (Moderator)Maria Buti (Moderator)Thomas Babor (Faculty)All EASL Studio Podcasts are available on...

In honour of International NASH Day, the final episode of EASL Studio season 4 is shedding light on non-alcoholic steatohepatitis (NASH), a disease with increasing global prevalence but low awareness. Faculty Zobair Younossi (Moderator)Alina M. Allen (Faculty)Sven Francque (Faculty)Vincent Wong (Faculty)Shira Zelber-Sagi (Faculty)All EASL Studio Podcasts are available on EASL Campus.

Non-alcoholic steatohepatitis (NASH) is rapidly emerging as a leading cause of chronic liver disease, presenting significant challenge due to the limited treatment options available. This EASL Studio JHEP Live aims to explore novel and promising treatments currently being evaluated for the treatment of NASH. In particular: ARO-HSD, an HSD17β13 inhibitor.PXL065 under evaluation in the DESTINY-1 trial.The investigation of an FXR agonist in fibrotic NASH as part of the LIVIFY trial.Faculty Prof....

Clinical evidence indicates that cigarette smoking negatively impacts the incidence and severity of fatty liver disease, fibrosis progression, hepatocellular carcinoma development, and the outcomes of patients with advanced liver disease. The underlying mechanisms are complex and involve different pathophysiological pathways including oxidative stress and oncogenic signals. To coincide with World No Tobacco Day, 31 May, this EASL Studio discusses some of the pathophysiological mechanisms that...

Collaborations are key in achieving scientific progress. The European Horizon COST Actions provide great opportunities to build, grant, and/or participate in pan-European collaborations in multidisciplinary topics, including liver diseases. This EASL Studio: Provides you with information about the COST Action programme.Discusses the structure of the drug-induced liver injury (DILI) and cholangiocarcinoma (CCA) working groups.Highlights the potential for collaborative work within this...

On 22 May 2023, policymakers, thought leaders, Permanent Mission Representatives to the UN, WHO staff, and people affected by liver disease will gather at the EASL Office in Geneva for the invitation-only event on the side-lines of the 76th World Health Assembly*: “Together for Better Liver Health: Mobilising Action for Fatty Liver Disease”. The aim of the event is to raise awareness on the need for action, and to call for a coordinated response to combat the global public health threat...

Hepatitis D is the most severe form of viral hepatitis infection, but fortunately, new treatments are on the horizon. This EASL Studio discusses: Which patients should be treated.Currently available treatment options.Treatment combinations and duration.New treatments in development.Faculty Prof. Heiner Wedemeyer (Moderator)Prof. Soo Aleman (Faculty)Prof. Pietro Lampertico (Faculty)Related episodes: S2E3: Interview with Stephan Urban – From bench to bedside: Process of developing the first...

International Nurses Day, 12 May, commemorates the birth of Florence Nightingale, considered to be the founder of modern nursing. EASL Studio is taking this opportunity to highlight the important role of nursing in the care of people with liver disease. Faculty Dr Kathryn Jack (Moderator)Mrs Michelle Clayton (Faculty)Mrs Núria Fabrellas (Faculty)Mrs Denise Schäfer (Faculty)Dr Patrizia Künzler-Heule (Faculty)All EASL Studio Podcasts are available on EASL Campus.

Although a longstanding recommendation, the use of albumin as an effective treatment for patients with cirrhosis and ascites has come under scrutiny with recently published studies creating confusion. This EASL Studio discusses, recent results from the MACHT, ATTIRE and PRECIOSA studies and try to shed some light on this controversial topic. Faculty Prof. Alastair O’Brien (Moderator)Prof. Aleksander Krag (Moderator)Prof. Paolo Caraceni (Faculty)Dr Elisa Pose (Faculty)Prof. Joan Clària...

Watch this EASL Studio for highlights from the Liver Cancer Summit 2023. Discover: How artificial Intelligence is being used to increase knowledge in the field of liver cancer.New markers in hepatocellular carcinoma beyond ultrasound.Updates in the field cholangiocarcinoma and rare liver diseases… and much more!Faculty Prof. Mathias Heikenwälder (Moderator)Prof. Josep Llovet (Faculty)Prof. Helen Reeves (Faculty)Related episodes: S3E16 – Liver cancer in 2022: Wrap-up & outlookS2E15 – JHEP...

Wilson’s disease is a rare autosomal recessive disorder of copper metabolism which is characterised by hepatic and neurological disease This episode of EASL Studio will: Cover the difficulties in diagnosing Wilson’s disease.Discuss treatment options and strategies.Explore the challenges faced by patients with Wilson’s disease.Faculty Prof. Emmanuel Tsochatzis (Moderator)Dr Wiebke Papenthin (Patient Perspective)Dr Aurélia Poujois (Faculty)Prof. Piotr Socha (Faculty)Related episodes: S4E7 –...

The EASL Policy Statement on liver cancer screening has recently been updated. In addition to addressing the updates, this episode of EASL Studio will discuss how risk-based surveillance of hepatocellular carcinoma (HCC) in patients suffering from cirrhosis is a cost effective strategy to increase benefits, reduce the harm of HCC surveillance. Faculty Prof. Thomas Berg (Moderator)Mr. Pietro Fiocchi (Faculty)Prof. Peter Jepsen (Faculty)Mrs. José Willemse (Patient Perspective) All EASL Studio...

Through widespread multidisciplinary collaboration, consortia and EU grants provide unique opportunities to address critical questions. What opportunities exist for early career scientist?Which elements are essential for success?How have these partnerships contributed to advancements in the field?Watch this episode of EASL Studio to find out. Faculty Prof. Thomas Berg (Moderator)Prof. Rajiv Jalan (Moderator)Prof. Minneke Coenraad (Faculty)Dr Cornelius Engelmann (Faculty)Prof. Pierre-Emmanuel...

The topic of liver transplantation for alcohol-related hepatitis is controversial. While some experts still recommend 6 months of alcohol abstinence before considering transplantation others advocate for early transplantation. Watch this episode to: Understand the epidemiology of alcohol-related hepatitis.Know which treatment options are available to these patientsFind out which patients may benefit from earl liver transplantation.Faculty Prof. Patrizia Burra (Moderator)Dr Giacomo Germani...

Liver biopsy has long been the gold standard for diagnosing NAFLD and NASH. However, it is an invasive  procedure that may not always be necessary. This episode of EASL Studio explored methods for screening, staging, and monitoring disease progression. Faculty Prof. Philip Newsome (Moderator)Prof. Laurent Castera (Faculty)Prof. Maja Thiele (Faculty)All EASL Studio Podcasts are available on EASL Campus.