"This condition is really overlooked. The point of the Monograph is that it should, hopefully, raise awareness." In the latest instalment of the ERS Monograph podcast series, Editorial Board member Holly Keir talks to James H. Hull, one of the Guest Editors of the Monograph on Complex Breathlessness. In a conversation that focuses on the need for robust investigation when faced with unexplained breathlessness, James and Holly discuss: the use of physiological tests and CPET for assessment; postural tachycardia syndrome and autonomic dysfunction; the importance of developing breathlessness clinics in the future; and therapy-based treatments, such as physiotherapy and speech and language therapy.