Episode 28 - Pharmacogenomics with Dr. Natasha Petry, PharmD, BCACP Natasha has a bachelor’s degree in Microbiology and graduated with a Doctor of Pharmacy in 2012 from North Dakota State University in Fargo, ND. She completed a post graduate Pharmacy Practice Residency at Trinity Health in Minot, ND and joined the faculty at NDSU as an Assistant Professor with a clinical appointment at Sanford Health. She is a board-certified Ambulatory Care Pharmacist and began working in the area of Pharmacogenomics in 2014. She is an affiliate member of the NIH funded Implementing GeNomics In practice (IGNITE) network. She currently works as a Pharmacogenetics Clinical Pharmacist for Sanford Imagenetics. In addition, she is pursuing a Master of Public Health degree. Natasha is a wife, mother to 2 beautiful girls, and enjoys attending sporting events. Pharmacogenomics: The genetics of how people metabolize (break down) medications. Genetic information can help guide the use of medication dosing and medication choice. Genetics looks at the enzymes that break down medications. Can help determine efficacy or utility, safety and/or dosing Still limited but growing rapidly- another “tool in the toolbox” Genetics does not change in a lifetime Cost can be limiting Currently useful in prescribing antidepressants, some pain medications, cholesterol medications (statins), clopidogrel (Plavix), warfarin Limitations: No standardization in lab testing regarding which allele variants are tested Cost Limited actionable results that impact a finite number of medications Genetic testing collected through blood, saliva, cells from the cheeks depending on lab used Variable insurance coverage: preemptive testing not likely covered, reactive is being covered more often Direct to consumer testing vs. laboratory (health system) derived testing Need Medical Geneticists and Pharmacists to help interpret information Health Pearl: Try out meal delivery kits for improved health Resource list: https://imaginetics.sandordhealth.org https://www.genome.gov/FAQ/Pharmacogenomics https://ghr.nlm.nih.gov/primer/genomicresearch/pharmacogenomics https://www.yourgenome.org/facts/what-is-pharmacogenomics https://nigms.nih.gov/education/pages/factsheet-pharmacogenomics.aspx https://www.cdc.gov/genomics/disease/pharma.htm https://pharmgkb.org/page/pharmacogenomics https://www.pharmkb/page/iAmACitizen Follow us on Facebook and Twitter: www.facebook.com/everythingdoc www.twitter.com/everythingdoc1