How good are we at predicting outcome in severe TBI? Do all patients do bad, or are there some that recover? On this episode Karl dives into the data to give us an update on what the data supports. Literature Referenced: What early predictions do we make? Barlow, P., Teasdale, G. (1986). Prediction of Outcome and the Management of Severe Head Injuries: The Attitudes of Neurosurgeons Neurosurgery 19(6), 989-991. https://dx.doi.org/10.1227/00006123-198612000-00014 How good are we at predicting outcomes in ICU patients? Kaufmann, M., Buchmann, B., Scheidegger, D., Gratzl, O., Radü, E. (1992). Severe head injury: should expected outcome influence resuscitation and first-day decisions? Resuscitation 23(3), 199-206. https://dx.doi.org/10.1016/0300-9572(92)90003-u Brain Trauma Foundation guidelines on prognosis in severe TBI https://www.braintrauma.org/guidelines/prognosis IMPACT calculator to model TBI outcome http://www.tbi-impact.org/ Updated practice guidelines on the management of patients with disorders of consciousness Giacino, J., Katz, D., Schiff, N., Whyte, J., Ashman, E., Ashwal, S., Barbano, R., Hammond, F., Laureys, S., Ling, G., Nakase-Richardson, R., Seel, R., Yablon, S., Getchius, T., Gronseth, G., Armstrong, M. (2018). Practice guideline update recommendations summary: Disorders of consciousness: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology; the American Congress of Rehabilitation Medicine; and the National Institute on Disability, Independent Living, and Rehabilitation Research Neurology 91(10), 10.1212/WNL.0000000000005926. https://dx.doi.org/10.1212/wnl.0000000000005926