In this in-depth episode, we dive headfirst into one of the most polarizing topics in modern gastrointestinal medicine - the heated debate between cold snare polypectomy (CSP) and hot snare polypectomy (HSP) techniques.  Our host provides a comprehensive overview of these two pivotal polyp removal methods, exploring their pros, cons, and appropriate use cases. We learn about: • The fundamentals of CSP and HSP  • European guideline recommendations for each technique based on polyp size • Comparative data on complete resection rates and complication profiles • Managing challenges like bleeding and tissue injury • The critical importance of polyp retrieval and histopathological analysis • Potential future advancements in endoscopic tools and techniques  • Adhering to best practices and clinical guidelines Key Takeaways: - CSP shows a superior safety profile for diminutive (5mm) and small (6-9mm) sessile polyps - HSP provides coagulation benefits for larger polyps (10-20mm) and bleeding control  - Both methods demonstrate comparable resection completeness for 4-10mm polyps - HSP carries higher risks like delayed bleeding and deep thermal injury - Polyp retrieval quality is high with both techniques for accurate diagnosis   - Technique choice depends on balancing polyp factors and patient needs - Ongoing research and new technologies will further refine polypectomy Whether you're a seasoned endoscopist or just getting started, this episode provides invaluable insights into optimizing polypectomy outcomes through the judicious application of CSP and HSP. Join us as we unpack this critical clinical debate. Links: Cold Snare vs Hot Snare: Polypectomy Factshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506415/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246601/https://www.gastroenterologyadvisor.com/colorectal-neoplasia/cold-vs-hot-snare-polypectomy-yields-more-favorable-outcomes-for-colorectal-polyps/ https://www.gastroendopod.com