Millions of Americans struggle with substance abuse - at great cost to themselves, their loved ones, and society overall. It's a huge burden that we can't address effectively, until we can characterize it fully. Is addiction a choice-based societal problem? Or is it a biologically driven health crisis? And how can research with animals inform therapeutic strategies for what seems to be a purely human phenomenon? Joining us today to discuss this and more is Dr. Edythe London, a pioneer in addiction research and treatment strategies, who continues to risk her own personal safety to minimize the suffering of others.