EDIT: THIS EPISODE WAS RECORDED, EDITED, AND RELEASED BEFORE PUR REBRAND AS FRIDAYS WITH FRANK. WE FELT THOUGH THAT THIS IS STILL PART OF WHO WE ARE AS WE GROW AND CHANGE, AND SO IT WILL STAY UP. It has been a bit, but in this episode, we decide to switch it from on M to the other, and go over some science. Apologies in advance, as there is a LOT of jargon in this episode, especially since we went over genetics, but it couldn't be helped. Don't worry though Frank was just as lost as the rest of you reading, researching, and talking about it. Also, Chase plays a prank on Teresa with a pillow, and Teresa finally admits why she is really on the podcast. Oh, and we finally got rid of the jarring transitions to an ad! References Glick, N. (2006), Dramatic reduction in self‐injury in Lesch–Nyhan disease following S‐adenosylmethionine administration. J Inherit Metab Dis,29: 687-687. doi:10.1007/s10545-006-0229-8 Michael Lesch, William L. Nyhan (1964). A familial disorder of uric acid metabolism and central nervous system function. The American Journal of Medicine. Volume 36 (4), pgs 561-570, https://doi.org/10.1016/0002-9343(64)90104-4. Lloyd, K.G., Hornykiewicz, O., Davidson, L., Shannak, K., et. al. (1981) Biochemical evidence of dysfunction of brain neurotransmitters in the Lesch-Nyhan Syndrome. The New England Journal of Medicine. doi:10.1056/NEJM198111053051902 Harris, J.C. (2018). Lesch-Nyhan syndrome and its variants: examining the behavioral and neurocognitive phenotype. Current Opinion in Psychiatry 31(2): pp 96-102. doi:https://doi.org/10.1097/YCO.0000000000000388 https://rarediseases.info.nih.gov/diseases/7226/lesch-nyhan-syndrome Preston, R. (2009). Panic in level 4: Cannibals, killer viruses, and other journeys to the edge of science. New York: Random House Trade Paperbacks. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/fridayswithfrank/message