Jo Ann Leal, PharmD (Twitter @JoJoPharmD) describes the key components of the drug supply chain and the impact of drug shortages, identifies common organizational strategies used to mitigate drug shortages and evaluates recent national efforts to stabilize the drug supply chain. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter! You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.