Meditation Hand Signs Download the Selfpause Affirmation App Prana mudra meditation hand signs are hands-on positions that increase the healing power of prana. These postures require preparation. Firstly, find a quiet place and close your eyes. You should also prepare your hands by rubbing them gently together. This will activate nerve endings and stimulate cells that are linked to various organs. There are several types of mudras. Each mudra has different benefits. Some promote specific qualities and others are more universal. For instance, one mudra will activate a different energy channel in the body than another. You might need different mudras for different yoga positions.