Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Cimetidine Trade Name Tagamet Indication Treatment of duodenal ulcers, GERD, heartburn, Zollinger Ellison syndrome, prevention of GI bleeding in critical patients. Action Inhibits action of histamine leading to inhibition of gastric acid secretion Therapeutic Class Antiulcer agent Pharmacologic Class Histamine H2 antagonist Nursing Considerations • Increases serum level of warfarin • Can lead to respiratory infection (green sputum) • Monitor for arrhythmias • May cause agranulocytosis, aplastic anemia • Monitor CBC during therapy • Take medication as directed • Instruct patient to increase fluid and fiber intake to decrease constipation