Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Codeine Trade Name Paveral Indication Management of pain, diarrhea, cough suppressant Action Binds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS. This depression also causes a decrease in the cough reflex and GI motility. Therapeutic Class Allergy, cold, cough remedy, antitussive, opioid analgesic Pharmacologic Class Opioid agonist Nursing Considerations • May cause alterations in mentation, hypotension, constipation, nausea, vomiting • Assess BP, pulse, and respiratory rate prior to administration and frequently during administration • Use caution if patient is receiving MAO Inhibitors • Narcan (naloxone) is the antidote for opioid agonists