Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Diphenoxylate/atropine Trade Name Lomotil Indication Treatment for diarrhea Action Inhibits GI motility via anticholinergic effects Therapeutic Class Antidiarrheal Pharmacologic Class Anticholinergic Nursing Considerations • Contraindicated with angle-closure glaucoma, dehydration • Structurally related to opioids so use caution with patients that have allergies to opioids • May cause constipation, tachycardia, dizziness, ileus • Monitor liver function as the medication is excreted by the liver • Ensure that client is taking medication as prescribed and not double dosing