Relapse in Schizophrenia: Why It Occurs, How Often It Occurs, and What We Can Do About It
Description
Drs John Kane and Jose Rubio-Lorente discuss relapse in schizophrenia — why it occurs, how often it occurs, and what we can do about it.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/969531). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals.
Resources
Schizophrenia https://www.medscape.com/resource/schizophrenia
Schizophrenia Clinical Presentation https://emedicine.medscape.com/article/288259-clinical
Natural Course of Schizophrenic Disorders: A 15-Year Follow-up of a Dutch Incidence Cohort https://academic.oup.com/schizophreniabulletin/article/24/1/75/1878027
Predictors of Relapse Following Response From a First Episode of Schizophrenia or Schizoaffective Disorder https://jamanetwork.com/journals/jamapsychiatry/fullarticle/204795
Five-Fold Increased Risk of Relapse Following Breaks in Antipsychotic Treatment of First Episode Psychosis https://www.sciencedirect.com/science/article/abs/pii/S0920996416304376?via%3Dihub
Long-term Continuity of Antipsychotic Treatment for Schizophrenia: A Nationwide Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530382/
Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29,823 Patients With Schizophrenia https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710250
Long-Acting Injectable Versus Oral Antipsychotics for the Maintenance Treatment of Schizophrenia: A Systematic Review and Comparative Meta-analysis of Randomised, Cohort, and Pre-Post Studies https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(21)00039-0/fulltext
Effect of Long-Acting Injectable Antipsychotics vs Usual Care on Time to First Hospitalization in Early-Phase Schizophrenia: A Randomized Clinical Trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364341/
Psychosis Relapse During Treatment With Long-Acting Injectable Antipsychotics in Individuals With Schizophrenia-Spectrum Disorders: An Individual Participant Data Meta-analysis https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(20)30264-9/fulltext
The Pharmacological Treatment of Schizophrenia: How Far Have We Come? https://onlinelibrary.wiley.com/doi/full/10.1002/pcn5.13
Striatal Functional Connectivity in Psychosis Relapse: A Hypothesis Generating Study https://www.sciencedirect.com/science/article/pii/S092099642100222X?via%3Dihub
Drs John M. Kane and Mitchell Arnovitz discuss assessment of patients for negative symptoms of schizophrenia and the potential of MDMA in alleviating these symptoms in supervised treatment settings.
Relevant disclosures can be found with the episode show notes on Medscape...
Published 07/20/23
Drs John M. Kane and Delbert G. Robinson discuss psychoeducation, treatment options, and possible side effects of medication for patients experiencing their first episode of schizophrenia.
Relevant disclosures can be found with the episode show notes on Medscape...
Published 06/21/23