Drs John M. Kane and Christoph U. Correll discuss the importance of ongoing assessment of psychiatric comorbidities in patients with schizophrenia and its impact on outcomes and treatment decisions. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/984483). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Schizophrenia https://www.medscape.com/resource/schizophrenia What Are the Major Metabolic and Neurologic Risks Associated With Antipsychotic Medications? https://www.medscape.com/viewarticle/969525 Trauma and Posttraumatic Stress Disorder (PTSD) in Patients With Schizophrenia or Schizoaffective Disorder https://pubmed.ncbi.nlm.nih.gov/19777347/ Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) https://www.psychiatry.org/psychiatrists/practice/dsm Relationship Between Obsessive Compulsive Symptomatology and Severity of Psychotic Symptoms in Schizophrenia: Meta-analysis and Meta-Regression Analysis https://pubmed.ncbi.nlm.nih.gov/36549240/ Clozapine-Induced Obsessive-Compulsive Symptoms: Mechanisms and Treatment https://pubmed.ncbi.nlm.nih.gov/30565908/ The Specific Phenotype of Depression in Recent Onset Schizophrenia Spectrum Disorders: A Symptom Profile and Network Comparison to Recent Onset Major Depressive Disorder Without Psychotic Features https://pubmed.ncbi.nlm.nih.gov/34942537/ Schizophrenia Comorbid With Panic Disorder: Evidence for Distinct Cognitive Profiles https://pubmed.ncbi.nlm.nih.gov/22417926/ Obsessive-Compulsive Disorder Comorbid With Schizophrenia and Bipolar Disorder https://pubmed.ncbi.nlm.nih.gov/30745688/ Depressive Symptoms in Schizophrenic Patients https://pubmed.ncbi.nlm.nih.gov/22112362/ Post-Psychotic Depression: An Updated Review of the Term and Clinical Implications https://pubmed.ncbi.nlm.nih.gov/35220306/ Mortality in People With Schizophrenia: A Systematic Review and Meta-analysis of Relative Risk and Aggravating or Attenuating Factors https://pubmed.ncbi.nlm.nih.gov/35524619/ Comorbid Major Depressive Disorder in Schizophrenia: A Systematic Review and Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/33252130/ The RAISE Early Treatment Program for First-Episode Psychosis: Background, Rationale, and Study Design https://pubmed.ncbi.nlm.nih.gov/25830446/ First Episode Psychosis With and Without the Use of Cannabis and Synthetic Cannabinoids: Psychopathology, Global Functioning and Suicidal Ideation and Antipsychotic Effectiveness https://pubmed.ncbi.nlm.nih.gov/36682093/ Cannabis Use Among Patients With Psychotic Disorders https://pubmed.ncbi.nlm.nih.gov/35348056/ Methamphetamine Psychosis: Epidemiology and Management https://pubmed.ncbi.nlm.nih.gov/25373627/ Demographic and Clinical Correlates of Substance Use Disorders in First Episode Psychosis https://pubmed.ncbi.nlm.nih.gov/28697856/ Why Do Patients With Schizophrenia Smoke? https://pubmed.ncbi.nlm.nih.gov/20051860