“So far, all vaccines in the market have shown great efficacy in reducing clinical signs associated to diseases caused by PCV-2, independently of the genotype present in the farm. Moreover, experimental data demonstrated the cross-protection of PCV-2a vaccines against the most widespread genotypes (PCV-2a, PCV-2b, and PCV-2d). Therefore, despite the significant number of genotypes described/proposed (PCV-2a to PCV-2i), it seems one single PCV-2 serotype would exist". Joaquim Segalés is full professor at the UAB and researcher at the IRTA-CReSA animal health research institute. He has been working with swine diseases for the last 28 years and he has also been working with zoonotic coronaviruses since 2014. He is co-author of more than 350 peer-reviewed publications, most of them on pig diseases and specifically on porcine circovirus diseases. Professor Segalés will share his wealth of experience on the evolution of the PCV2 virus and what that means in terms of diagnosis, understanding the evolving epidemiology and the control using vaccines. How can we make the right decisions on the farm?