Climate change is possibly the major threat that planet earth is experiencing in this century with potential catastrophic consequences. As the planet warms, the change in weather patterns is affecting the microbial ecology in such a manner that humans are facing new health threats including emerging diseases and facing species of organisms that are more likely to survive these new climatic conditions and resist clinically useful antimicrobials. Topics discussed: The global threat of global warming. Climate change and change sin microbial ecology. The consequences of climate change and emergence of new infectious diseases and antimicrobial resistance patterns. Guests: Arturo Casadeval MD, Bloomberg Distinguished Professor, Alfred & Jill Sommer Professor and Chair Department of Molecular Microbiology & Immunology, Johns Hopkins Bloomberg School of Public Health. Editor in Chief of mBio, Member of the National Academy of Sciences